Avibactam Impurity 46
- CAS No.
- 1804915-68-1
- Chemical Name:
- Avibactam Impurity 46
- Synonyms
- WCK4234;Avibactam Impurity 46;Avibactam Impurity 67 Sodium Salt;sodium (2R,5R)-2-cyano-7-oxo-6-azabicyclo[3.2.1]octan-6-yl sulfate;Sulfuric acid, mono[(1R,2S,5R)-2-cyano-7-oxo- 1,6-diazabicyclo[3.2.1]oct-6-yl] ester, sodium salt (1:1);inhibit,carbapenemases,antibacterial,KPC enzymes,diazabicyclooctanes (DBOs),Enterobacteriaceae,Bacterial,Inhibitor
- CBNumber:
- CB14869651
- Molecular Formula:
- C7H10N3NaO5S
- Molecular Weight:
- 271.22
- MDL Number:
- MOL File:
- 1804915-68-1.mol
Avibactam Impurity 46 Chemical Properties,Uses,Production
Biological Activity
WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibits class A, C, and D β-lactamases activity. WCK-4234 lacks direct antibacterial activity. WCK-4234 potentiates imipenem and meropenem against Enterobacteriaceae with OXA-48/OXA-181 or KPC enzymes, or with combinations of impermeability and AmpC or ESBL activity. WCK-4234 distinctively overcomes resistance mediated by OXA-type carbapenemases[1][2].
References
[1]. Iregui A, et al. Activity of Meropenem with a Novel Broader-Spectrum β-Lactamase Inhibitor, WCK 4234, against Gram-Negative Pathogens Endemic to New York City. Antimicrob Agents Chemother. 2019 Dec 20;64(1):e01666-19. [2]. Mushtaq S, et al. WCK 4234, a novel diazabicyclooctane potentiating carbapenems against Enterobacteriaceae, Pseudomonas and Acinetobacter with class A, C and D β-lactamases. J Antimicrob Chemother. 2017 Jun 1;72(6):1688-1695.
Avibactam Impurity 46 Preparation Products And Raw materials
Raw materials
Preparation Products
Avibactam Impurity 46 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Moco Chemical Co., Ltd. | 18627756402 | 3001051413@qq.com | China | 10009 | 58 |
| Shenzhen Hengfeng Wanda Pharmaceutical Technology Co., Ltd | 755-22677922-801 18126518403 | 2851922760@qq.com | China | 5043 | 58 |
| Hebei Weite Medical Technology Co., Ltd | 13180081292 | contact@wetogethermed.com | China | 7264 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | 0755-66853366 15920483169 | sales@chem-strong.com | China | 18810 | 58 |
| Shenzhen Roark Pharma-Tec Co., Ltd. | 13128912434 | 2880126944@qq.com | China | 2579 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| guoyungurui | 18162595016 | 3287908757@qq.com | China | 10015 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12007 | 58 |