N-Isopropylacrylamide
- CAS No.
- 2210-25-5
- Chemical Name:
- N-Isopropylacrylamide
- Synonyms
- NIPAM;NIPAAm;acryL;Isopropyl acrylamide;N-isopropylacrylamide ,99%;N-(1-methylethyl)-2-Propenamide;FITC-PEG;AKOS 91289;N-IsopropyL;polyNIPAM-BA
- CBNumber:
- CB1494912
- Molecular Formula:
- C6H11NO
- Molecular Weight:
- 113.16
- MDL Number:
- MFCD00041913
- MOL File:
- 2210-25-5.mol
- MSDS File:
- SDS
| Melting point | 60-63 °C(lit.) |
|---|---|
| Boiling point | 89-92 °C2 mm Hg(lit.) |
| Density | 1.0223 (rough estimate) |
| refractive index | 1.4210 (estimate) |
| storage temp. | 2-8°C |
| pka | 14.83±0.46(Predicted) |
| form | Crystalline Powder or Crystals |
| color | White to light yellow |
| PH | pH(50g/l, 25℃) : 7.8～10.0 |
| Water Solubility | Slightly soluble in water. |
| InChIKey | QNILTEGFHQSKFF-UHFFFAOYSA-N |
| LogP | 0.278 (est) |
| CAS DataBase Reference | 2210-25-5(CAS DataBase Reference) |
| FDA UNII | B7GFF17L9U |
| NIST Chemistry Reference | Acrylamide, n-isopropyl-(2210-25-5) |
| EPA Substance Registry System | 2-Propenamide, N-(1-methylethyl)- (2210-25-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AS3675000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29241990 | |||||||||
| NFPA 704 |
|
N-Isopropylacrylamide price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 415324 | N-Isopropylacrylamide 97% | 2210-25-5 | 10g | $47.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 415324 | N-Isopropylacrylamide 97% | 2210-25-5 | 50g | $166 | 2024-03-01 | Buy |
| TCI Chemical | I0401 | N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC) | 2210-25-5 | 25g | $54 | 2024-03-01 | Buy |
| TCI Chemical | I0401 | N-Isopropylacrylamide (stabilized with MEHQ) >98.0%(GC) | 2210-25-5 | 100g | $99 | 2024-03-01 | Buy |
| Alfa Aesar | H66262 | N-Isopropylacrylamide, 97% | 2210-25-5 | 25g | $74.2 | 2024-03-01 | Buy |
N-Isopropylacrylamide Chemical Properties,Uses,Production
Description
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).
Chemical Properties
white to light yellow crystalline powder or
Uses
NIPAM can be used to prepare poly(NIPAM) for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.
Uses
Binders in textiles, paper, adhesives, detergents, cosmetics.
N-Isopropylacrylamide is used to produce poly(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA or pNIPAm) thermo sensitive polymer- or copolymer-based hydrogels. Polymers that contain NIPAM shrink dramatically above 33°C. Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
Application
N-Isopropylacrylamide (NIPAM) can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.
Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.
General Description
N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties. These properties include temperature based volumetric and phase changes, which change when the temperature of the solution reaches a lower critical solution temperature (LCST).
Flammability and Explosibility
Not classified
Purification Methods
Fractionate the amide under reduced pressure, and recrystallise the solid distillate from hexane (m 59o), *C6H6 (m 62o) or *C6H6/hexane (m 62-63o). Store it with 0.05% of 4-tert-butylcatechol. It is used for making water soluble swellable hydrogels. [Beilstein 4 IV 517.]
N-Isopropylacrylamide Preparation Products And Raw materials
Raw materials
1of5
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18458 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-13102810335 | admin@hbsaisier.cn | China | 424 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2966 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
View Lastest Price from N-Isopropylacrylamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-19 | N-Isopropylacrylamide
2210-25-5
|
US $0.00 / kg | 1kg | 98% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-04-12 | N-Isopropylacrylamide
2210-25-5
|
US $6.00-3.00 / KG | 1KG | More than 99% | 20000kg | Hebei Saisier Technology Co., LTD | |
 |
2024-01-06 | N-Isopropylacrylamide
2210-25-5
|
US $0.00 / kg | 1kg | 99% | 1000000 | Hebei Jingbo New Material Technology Co., Ltd |
-
- N-Isopropylacrylamide
2210-25-5
- US $0.00 / kg
- 98%
- Jinan Finer Chemical Co., Ltd
-
- N-Isopropylacrylamide
2210-25-5
- US $6.00-3.00 / KG
- More than 99%
- Hebei Saisier Technology Co., LTD
-
- N-Isopropylacrylamide
2210-25-5
- US $0.00 / kg
- 99%
- Hebei Jingbo New Material Technology Co., Ltd