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Pentoxyverine

Pentoxyverine
Pentoxyverine structure
CAS No.
77-23-6
Chemical Name:
Pentoxyverine
Synonyms
Urex;ucb2543;Atussil;Tuclase;Sedotussin;u.c.b.2543;U.C.B. 2543;Pentoxiverin;Pentoxyverin;CARETAPENTANE
CBNumber:
CB1497317
Molecular Formula:
C20H31NO3
Formula Weight:
333.46
MOL File:
77-23-6.mol

Pentoxyverine Properties

Boiling point:
165-170 °C (1.33Pa)
Density 
1.048±0.06 g/cm3(Predicted)
refractive index 
1.4990-1.5010
pka
9.69±0.25(Predicted)
CAS DataBase Reference
77-23-6(CAS DataBase Reference)
FDA UNII
32C726X12W
NIST Chemistry Reference
1-Cyclopentanecarboxylate, 2-(diethylaminoethoxy)ethyl-1-phenyl-(77-23-6)
SAFETY
  • Risk and Safety Statements
Toxicity LD50 oral in rat: 150mg/kg

Pentoxyverine Chemical Properties,Uses,Production

Originator

Asthma ,Nichiiko

Manufacturing Process

1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.

brand name

Toclase (Pfizer).

Therapeutic Function

Antitussive

Pentoxyverine Preparation Products And Raw materials

Raw materials

Preparation Products


Pentoxyverine Suppliers

Global( 109)Suppliers
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ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26734 60
Hubei Jusheng Technology Co.,Ltd.
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Xiamen AmoyChem Co., Ltd
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Shanghai Longyu Biotechnology Co., Ltd.
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HENAN BON INDUSTRIAL CO.,LTD
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Shaanxi Dideu Medichem Co. Ltd
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Zhuozhou Wenxi import and Export Co., Ltd
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SIMAGCHEM CORP
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View Lastest Price from Pentoxyverine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-23 Pentoxyverine
77-23-6
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-07-10 Pentoxyverine
77-23-6
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
2021-07-02 Pentoxyverine
77-23-6
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

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