PHENAMIL METHANESULFONATE
- CAS No.
- 1161-94-0
- Chemical Name:
- PHENAMIL METHANESULFONATE
- Synonyms
- MHPIZTURFVSLTJ-UHFFFAOYSA-N;2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-, methanesulfonate (1:1)
- CBNumber:
- CB1502107
- Molecular Formula:
- C13H16ClN7O4S
- Molecular Weight:
- 401.8
- MDL Number:
- MFCD00274070
- MOL File:
- 1161-94-0.mol
storage temp. | 2-8°C |
---|---|
solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble2.5mg/mL |
form | solid |
color | yellow |
CAS DataBase Reference | 1161-94-0 |
PHENAMIL METHANESULFONATE price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P203 | Phenamil methanesulfonate salt solid | 1161-94-0 | 5mg | $130 | 2024-03-01 | Buy |
Sigma-Aldrich | P203 | Phenamil methanesulfonate salt solid | 1161-94-0 | 25mg | $177.6 | 2024-03-01 | Buy |
Cayman Chemical | 14308 | Phenamil (methanesulfonate) ≥98% | 1161-94-0 | 5mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 14308 | Phenamil (methanesulfonate) ≥98% | 1161-94-0 | 10mg | $86 | 2024-03-01 | Buy |
Cayman Chemical | 14308 | Phenamil (methanesulfonate) ≥98% | 1161-94-0 | 50mg | $357 | 2024-03-01 | Buy |
PHENAMIL METHANESULFONATE Chemical Properties,Uses,Production
Chemical Properties
off-white to yellow solid
Uses
Phenamil methanesulfonate salt has been used:
- to stimulate adipocyte differentiation in 3T3 cells
- to test its effect on lateral flagella expression in Vibrio shilonii
- in nanoparticle preparation to test its effect on osteo/odontoblastic differentiation
Uses
Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte
General Description
Phenamil, a derivative of amiloride is an inhibitor of sodium channels including acid sensing ion channel (ASIC) and epithelial sodium channels (ENaC).
Biochem/physiol Actions
Phenamil is an inducer of peroxisome proliferator-activated receptor γ (PPARγ) and inhibits diamine oxidase. By favoring tribbles homolog 3 (Trb3) expression, phenamil holds therapeutic potential to treat pulmonary artery hypertension (PAH) and idiopathic PAH. It is also a bone morphogenetic protein (BMP) activator, which favors osteogenesis and odontogenesis of stem cells.
storage
Store at +4°C
PHENAMIL METHANESULFONATE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3069 | 58 | |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |