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N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE

CAS No.
147795-39-9
Chemical Name:
N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE
Synonyms
3-oxo-C8-HSL;N-(β-Ketooctanoyl)-L-homoserine;N-(3-Oxooctanoyl)-L-homoserine la;3-oxo-N-[(3S)-2-oxooxolan-3-yl]octanamide;N-(beta-oxooctan-1-oyl)homoserine lactone;N-(beta-Oxooctan-1-oyl)-L-homoserine lactone;(S)-3-oxo-N-(2-oxotetrahydrofuran-3-yl)octanaMide;Octanamide, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-;inhibit,signal,Agrobacterium,Inhibitor,N 3 Oxo octanoyl L homoserine lactone,quorum-sensing,N3OxooctanoylLhomoserine lactone
CBNumber:
CB1504055
Molecular Formula:
C12H19NO4
Molecular Weight:
241.28
MDL Number:
MFCD08277025
MOL File:
147795-39-9.mol
MSDS File:
SDS
Last updated:2023-09-04 15:50:00

N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE Properties

Melting point 54-60 °C
Boiling point 490.1±45.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility chloroform: 50 mg/mL, clear, colorless
form white powder
pka 11.09±0.46(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich O1764 N-(3-Oxooctanoyl)-L-homoserine lactone ≥97% (HPLC), white powder 147795-39-9 10mg $84.5 2024-03-01 Buy
Sigma-Aldrich O1764 N-(3-Oxooctanoyl)-L-homoserine lactone ≥97% (HPLC), white powder 147795-39-9 100mg $389 2024-03-01 Buy
Cayman Chemical 10011206 N-3-oxo-octanoyl-L-Homoserine lactone ≥98% 147795-39-9 5mg $38 2024-03-01 Buy
Cayman Chemical 10011206 N-3-oxo-octanoyl-L-Homoserine lactone ≥98% 147795-39-9 10mg $66 2024-03-01 Buy
Cayman Chemical 10011206 N-3-oxo-octanoyl-L-Homoserine lactone ≥98% 147795-39-9 25mg $153 2024-03-01 Buy
Product number Packaging Price Buy
O1764 10mg $84.5 Buy
O1764 100mg $389 Buy
10011206 5mg $38 Buy
10011206 10mg $66 Buy
10011206 25mg $153 Buy

N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE Chemical Properties,Uses,Production

Description

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. In the gram-negative bacterium A. tumefaciens, N-3-oxo-octanoyl-L-homoserine lactone promotes the expression of the transcriptional activator (and LuxR homolog) TraR.

Uses

N-3-oxo-octanoyl-L-Homoserine lactone is a reagent that promotes the expression of the transcriptional activator.

Uses

N-(3-Oxooctanoyl)-L-homoserine lactone has been used to study the effects of pH, temperature and salinity on extracellular polymeric substances (EPS) of Pseudomonas aeruginosa biofilm.

General Description

N-(3-Oxooctanoyl)-L-homoserine lactone is a common quorum sensing (QS) signal.

Biochem/physiol Actions

N-(3-Oxooctanoyl)-L-homoserine lactone stimulates the tra gene expression. It is an autoinducer and potent antagonist.

N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE Suppliers

Global( 32)Suppliers
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TargetMol Chemicals Inc.
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LEAPCHEM CO., LTD.
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Syntechem Co.,Ltd info@syntechem.com China 12990 57
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Cangzhou Enke Pharma-tech Co., Ltd. 0317-5296180 15533709196 sale@enkepharma.com China 1652 55

N-(3-OXOOCTANOYL)-L-HOMOSERINE LACTONE Spectrum

N-(beta-Oxooctan-1-oyl)-L-homoserine lactone N-(beta-oxooctan-1-oyl)homoserine lactone N-(β-Ketooctanoyl)-L-homoserine (S)-3-oxo-N-(2-oxotetrahydrofuran-3-yl)octanaMide Octanamide, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]- 3-oxo-C8-HSL 3-oxo-N-[(3S)-2-oxooxolan-3-yl]octanamide N-(3-Oxooctanoyl)-L-homoserine la inhibit,signal,Agrobacterium,Inhibitor,N 3 Oxo octanoyl L homoserine lactone,quorum-sensing,N3OxooctanoylLhomoserine lactone 147795-39-9