ChemicalBook >> CAS DataBase List >>RX-37
RX-37
- CAS No.
- 1627715-60-9
- Chemical Name:
- RX-37
- Synonyms
- RX-37;5H-Pyrido[4,3-b]indole, 1-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-
- CBNumber:
- CB15867384
- Molecular Formula:
- C24H23N5O2
- Molecular Weight:
- 413.47
- MDL Number:
- MFCD30532616
- MOL File:
- 1627715-60-9.mol
Last updated:2023-03-31 09:12:58
RX-37 Chemical Properties,Uses,Production
Description
RX-37 is a potent BET inhibitor. RX-37 binds to BET bromodomain proteins (BRD2, BRD3, and BRD4) with Ki values of 3.2-24.7 nM and demonstrates high selectivity over other non-BET bromodomain-containing proteins. RX-37 potently and selectively inhibits cell growth in human acute leukemia cell lines harboring the rearranged mixed lineage leukemia 1 gene. RX-37 represents a promising lead compound for the development of a new class of therapeutics for the treatment of human cancer and other conditions.
RX-37 Preparation Products And Raw materials
Raw materials
Preparation Products
RX-37 Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12007 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 58 |
| TargetMol Chemicals Inc. | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 58 |
RX-37
5H-Pyrido[4,3-b]indole, 1-(3-cyclopropyl-5-methyl-1H-pyrazol-4-yl)-7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-
1627715-60-9