ChemicalBook >> CAS DataBase List >>5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE

CAS No.
27406-31-1
Chemical Name:
5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE
Synonyms
MHY-1685;IFLAB-BB F1208-0006;5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID;5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID;5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE;5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione;2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]-;MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin
CBNumber:
CB1669325
Molecular Formula:
C11H8N2O4
Molecular Weight:
232.19
MDL Number:
MFCD00117979
MOL File:
Mol file
MSDS File:
SDS
Last updated:2023-07-05 08:28:19

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Properties

storage temp. Store at -20°C
solubility DMSO : 62.5 mg/mL (269.18 mM; Need ultrasonic)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H319-H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501-P264-P280-P305+P351+P338-P337+P313P

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S135925 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Aldrich 27406-31-1 50mg $29.8 2024-03-01 Buy
Product number Packaging Price Buy
S135925 50mg $29.8 Buy

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Chemical Properties,Uses,Production

Biological Activity

MHY-1685, a novel mammalian target of rapamycin (mTOR) inhibitor, provides opportunities to improve hCSC-based myocardial regeneration.

References

[1]. Park JH, et al. Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair. Exp Mol Med. 2021 Sep;53(9):1423-1436.

67-52-7
123-08-0
27406-31-1
Synthesis of 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE from Barbituric acid and 4-Hydroxybenzaldehyde

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Preparation Products And Raw materials

Raw materials

Preparation Products

5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Suppliers

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IFLAB-BB F1208-0006 5-(4-HYDROXYBENZYLIDENE)BARBITURIC ACID 5-(4-HYDROXYBENZYLIDENE)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE 5-(4-HYDROXY-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE 5-(4-HYDROXYBENZYLIDENE)BARBUTIRIC ACID 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(4-hydroxyphenyl)methylene]- 5-(4-hydroxyphenyl)methylenehexahydropyrimidine-2,4,6-trione MHY-1685 MHY-1685,MHY1685,MHY 1685,inhibit,mTOR,Inhibitor,Mammalian target of Rapamycin 27406-31-1