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heparinase I

CAS No.
9025-39-2
Chemical Name:
heparinase I
Synonyms
HEPARINASE;Neutralase;EC 4.2.2.7;HEPARINASE I;Lyase, heparin;HEPARIN LYASE I;Heparinase I - 0.1 IU;Heparin lyaseI, Heparinase;Lyophilized powder stabilized with appro;Native Flavobacterium heparinum Heparinase I
CBNumber:
CB1675289
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00131317
MOL File:
Mol file
Last updated:2022-12-21 16:56:50

heparinase I Properties

storage temp. -20°C
FDA UNII JLH8O457FC

SAFETY

Risk and Safety Statements

WGK Germany  3

heparinase I price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H2519 Heparinase I from Flavobacterium heparinum Lyophilizedpowderstabilizedwithapprox.25%bovineserumalbumin,≥200?units/ 9025-39-2 50units $371 2024-03-01 Buy
Sigma-Aldrich H2519 Heparinase I from Flavobacterium heparinum Lyophilizedpowderstabilizedwithapprox.25%bovineserumalbumin,≥200?units/ 9025-39-2 100units $636 2024-03-01 Buy
Sigma-Aldrich H2519 Heparinase I from Flavobacterium heparinum Lyophilizedpowderstabilizedwithapprox.25%bovineserumalbumin,≥200?units/ 9025-39-2 250units $1430 2024-03-01 Buy
Product number Packaging Price Buy
H2519 50units $371 Buy
H2519 100units $636 Buy
H2519 250units $1430 Buy

heparinase I Chemical Properties,Uses,Production

Uses

Heparinase I from Flavobacterium heparinum has been used:

  • in the digestion of plasma samples
  • to study the effect of medium, washing and sonication on the infectivity of Chlamydia pneumonia
  • in enzymatic removal of heparan sulfate from the surface of human rhabdomyosarcoma cells

Biochem/physiol Actions

Heparinase I from Flavobacterium heparinum acts by cleaving the α-glycoside linkage at AT III binding site in heparin. This results in small oligosaccharide fragments and heparinase I neutralizes the protein′s action of anticoagulation. Therefore it might replace the use of protamine in reversing heparin induced anticoagulation after coronary artery bypass surgery. Heparinase I possesses a half-life of 15-18 minutes.

heparinase I Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 24)Suppliers
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Creative Enzymes
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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Raw material medicin reagent co.,Ltd 025-57798860 sales@njromanme.com China 4534 58
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HEPARIN LYASE I HEPARINASE HEPARINASE I EC 4.2.2.7 Neutralase Lyase, heparin Heparin lyaseI, Heparinase HeparinaseI from Flavobacterium heparinum,Heparin lyaseI, Heparinase Heparin lyase from Bacteroides thetaiotaomicron, Recombinant Heparinase I from Flavobacterium heparinum, Recombinant Native Flavobacterium heparinum Heparinase I Heparinase I from Bacteroides eggerthii, Recombinant Heparinase I - 0.1 IU Lyophilized powder stabilized with appro 9025-39-2 Enzymes, Inhibitors, and Substrates Carbohydrate Hydrolysis Carbohydrate hydrolysis & PTM analysis BioChemical Application Index Biochemicals and Reagents