BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE
- CAS No.
- 116673-45-1
- Chemical Name:
- BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE
- Synonyms
- TRANS-BTP DIOXOLANE;BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;(2R,4R)-rel-2,4-Bis(3,4,5-triMethoxyphenyl)-1,3-dioxolane;TRANS-(+/-)-2,4-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;(+/-) TRANS-2,5-BIS(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE;1,3-Dioxolane, 2,4-bis(3,4,5-trimethoxyphenyl)-, (2R,4R)-rel-
- CBNumber:
- CB1683314
- Molecular Formula:
- C21H26O8
- Molecular Weight:
- 406.43
- MDL Number:
- MFCD00155367
- MOL File:
- 116673-45-1.mol
BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J67356 | (±)-trans-2,5-Bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane | 116673-45-1 | 1mg | $56.4 | 2021-12-16 | Buy |
| Alfa Aesar | J67356 | (±)-trans-2,5-Bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane | 116673-45-1 | 5mg | $220 | 2021-12-16 | Buy |
| Cayman Chemical | 60950 | (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane ≥98% | 116673-45-1 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 60950 | (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane ≥98% | 116673-45-1 | 5mg | $182 | 2024-03-01 | Buy |
| Cayman Chemical | 60950 | (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane ≥98% | 116673-45-1 | 10mg | $322 | 2024-03-01 | Buy |
BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Chemical Properties,Uses,Production
Uses
A potent and selective platlet activating factor
Biological Activity
(±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane, also known as trans-btp dioxolane, is a paf receptor antagonist [1].platelet activating factor (paf), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. paf also stimulates the production of active oxygen species by human monocyte - derived macrophages. paf play important roles in a variety of pathophysiological states including acute allergy, inflammation, asthma, gastrointestinal ulceration, and toxic shock [1].(±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane is a paf receptor antagonist. in the rabbit washed platelet assay, (±)trans-2,5-bis-(3,4,5-trimethoxyphenyl)-1,3-dioxolane showed good competitive paf antagonism with ki value of 0.3 μm, whereas the cis-isomer was much less active.
References
[1]. corey, e.j.,chen, c.p., and parry, m.j. dual binding modes to the receptor for platelet activating factor (paf) of anti-paf trans-2,5-diarylfurans. tetrahedron letters 29, 2899-2902 (1988).
BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Preparation Products And Raw materials
Raw materials
Preparation Products
BIS-(3,4,5-TRIMETHOXYPHENYL)-1,3-DIOXOLANE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6018 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
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