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5-Bromouridine

5-Bromouridine structure

CAS No.: 957-75-5

Chemical Name:: 5-Bromouridine

Synonyms: 5-BrU;5-Br-rU;5-Br-Ur;5-Br-Uridine;5-bromo-uridin;5-BROMOURIDINE;5'-BROMOURIDINE;5-Bromo-D-uridine;Uridine, 5-bromo-;5-Bromouridine,98%

CBNumber:: CB1683763

Molecular Formula:: C9H11BrN2O6

Molecular Weight:: 323.1

MDL Number:: MFCD00006528

MOL File:: 957-75-5.mol

MSDS File:: SDS

Last updated:2023-08-10 17:57:44

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5-Bromouridine Properties

Melting point	180-182 °C (dec.) (lit.)
alpha	-11 º (c=2 in H2O)
Density	1.9322 (rough estimate)
refractive index	1.6520 (estimate)
storage temp.	-20°C
solubility	Water (Sonicated)
form	Solid
pka	7.73±0.10(Predicted)
color	Off-White
optical activity	[α]22/D 11°, c = 2 in H2O
Water Solubility	Insoluble in water.
BRN	33664
CAS DataBase Reference	957-75-5(CAS DataBase Reference)
FDA UNII	KEY8PG1BRC

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02

Signal word

Danger

Hazard statements

H225

Precautionary statements

P210-P403+P235

Safety Statements

22-24/25

WGK Germany

RTECS

YU7300000

HS Code

29349990

NFPA 704

	1
0		0

5-Bromouridine price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	850187	5-Bromouridine 98%	957-75-5	250mg	$45.3	2024-03-01	Buy
Sigma-Aldrich	850187	5-Bromouridine 98%	957-75-5	1g	$112	2024-03-01	Buy
TCI Chemical	B0666	5-Bromouridine >99.0%(HPLC)	957-75-5	1g	$89	2024-03-01	Buy
TCI Chemical	B0666	5-Bromouridine >99.0%(HPLC)	957-75-5	100mg	$25	2024-03-01	Buy
Alfa Aesar	A18507	5-Bromouridine, 98%	957-75-5	0.25g	$24.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
850187	250mg	$45.3	Buy
850187	1g	$112	Buy
B0666	1g	$89	Buy
B0666	100mg	$25	Buy
A18507	0.25g	$24.65	Buy

5-Bromouridine Chemical Properties,Uses,Production

Description

5-Bromouridine is an energy-related metabolite that is a precursor of uridine. 5-Bromouridine binds to the nuclear DNA in cells, where it can act as a transcriptional regulator. 5-Bromouridine is used in the treatment of malignant brain tumors, where it can inhibit tumor growth by binding to the dna of cancer cells and preventing the synthesis of proteins required for cell division.

Chemical Properties

WHITE FINE POWDER

Uses

5-Bromouridine is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry. It possesses anti-viral activity and inhibits the activity of viruses such as human immunodeficiency virus.

Uses

5-Bromouridine is a uridine (U829910) derivative and is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry.

Definition

ChEBI: A uridine having a bromo substituent at the 5-position.

Purification Methods

Recrystallise it from 96% EtOH. UV max 279nm (log 3.95)in 2O pH 1.9. RF in n -BuOH/AcOH/H2O (4:4:1) is 0.49; in n-BuOH/EtOH/H2O (40:11:9) it is 0.46 and in isoPrOH/25%NH3/H2O (7:1:2) it is 0.53 using Whatman No 1 paper. [Pryst.s & Sorm Collect Czech Chem Commmun 29 2956 1964, Beilstein 31 H 24.]

5-Bromouridine synthesis

Synthesis of 5-Bromouridine from Guanosine

5-Bromouridine Preparation Products And Raw materials

Raw materials

beta-D-Ribofuranose 1,2,3,5-tetraacetate 2',3',5'-Tri-O-acetyluridine 5-Bromouracil Uridine Guanosine

Preparation Products

(3R)-3,4,5,6-Tetrahydro-4β,5β-dihydroxy-3β,6β-epoxy-2H,8H-pyrimido[6,1-b][1,3]oxazocine-8,10(9H)-dione

5-Bromouridine Suppliers

Global( 231)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
career henan chemical co	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
Antai Fine Chemical Technology Co.,Limited	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 5-Bromouridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-11	5-Bromouridine 957-75-5	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-04-07	5-Bromouridine 957-75-5	US $10.00 / KG	1KG	99%	10 mt	Hebei Guanlang Biotechnology Co., Ltd.
2022-09-24	5-Bromouridine 957-75-5	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

5-Bromouridine
957-75-5
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

5-Bromouridine
957-75-5
US $10.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

5-Bromouridine
957-75-5
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

5-Bromouridine Spectrum

5-Bromouridine(957-75-5)MS 5-Bromouridine(957-75-5)¹HNMR 5-Bromouridine(957-75-5)¹³CNMR 5-Bromouridine(957-75-5)IR1 5-Bromouridine(957-75-5)IR2 5-Bromouridine(957-75-5)Raman

957-75-5(5-Bromouridine)Related Search:

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Ribavirin 5-Fluorocytidine 1-beta-D-Arabinofuranosyluracil Uracil Doxifluridine

Cytidine PROTOVERATRINE B 2'-DEOXY-5-BROMOURIDINE 5-bromouridine-5'-monophosphate 2'-DEOXY-2'-BROMO-URIDINE

5-bromouridine 2',3',5'-Triacetate,2',3',5'-Triacetyl-5-bromouridine 5-BROMOURIDINE 5'-TRIPHOSPHATE SODIUM SALT 2'-O-METHYL-5-BROMO-U CEP

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1-beta-ribofuranosyl-5-bromo-uracil 5-bromo-uridin 5-Bromouridine,98% 5-Bromouridine, 99+% 5-bromouracil-1-β-d-ribofuranoside 5-Bromo-D-uridine 5-BROMO-URIDINE(5-BRU) 5-BROMOURIDINE (5-BROMOURACIL-1-β-D-RIBOFURANOSIDE: 5-BRU) 5-BROMOURIDINE extrapure 5-Bromouracil-1-β-D-ribofuranoside, 5-Bromouridine 5-Bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 5-BrU 5-broMo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione 5-broMo-1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyriMidine-2,4-dione 5-Br-rU 5-BroMo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3 5-Br-Uridine 5-BROMOURACIL-1-BETA-D-RIBOFURANOSIDE (-)-5-BROMOURIDINE 5'-BROMOURIDINE 5-BROMOURIDINE 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1 5-Br-Ur 5-Bromouridine > Uridine, 5-bromo- 5-Bromouridine USP/EP/BP 957-75-5 C9H11BrN2O6 C9H11N2O6Br Specialty Synthesis Oligonucleotide Synthesis Nucleosides Pyridines, Pyrimidines, Purines and Pteredines Biochemistry Nucleosides and their analogs Nucleosides, Nucleotides & Related Reagents