ChemicalBook >> CAS DataBase List >>Synephrine hydrochloride
Synephrine hydrochloride
- CAS No.
- 5985-28-4
- Chemical Name:
- Synephrine hydrochloride
- Synonyms
- SYNEPHRINE HCL;JACS-5985-28-4;UNII-EN5D1IH09S;Synephrine HCl 98%min;N-METHYL OCTOPAMINE HCL;Sympathol hydrochloride;Synephrine hydrochlorid;SYNEPHRINE HYDROCHLORIDE;Synephrine/Synephrine Hcl;(±)-Oxedrine hydrochloride
- CBNumber:
- CB1690109
- Molecular Formula:
- C9H14ClNO2
- Molecular Weight:
- 203.67
- MDL Number:
- MFCD00050566
- MOL File:
- 5985-28-4.mol
- MSDS File:
- SDS
Last updated:2024-04-24 17:21:45
| Melting point | 147-150°C |
|---|---|
| storage temp. | Refrigerator |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Off-White to Pale Beige |
| InChI | InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-2-4-8(11)5-3-7;/h2-5,9-12H,6H2,1H3;1H |
| InChIKey | COTCEGYSNTWJQV-UHFFFAOYSA-N |
| SMILES | C1(=CC=C(O)C=C1)C(O)CNC.Cl |
| LogP | -0.030 (est) |
| CAS DataBase Reference | 5985-28-4(CAS DataBase Reference) |
| FDA UNII | EN5D1IH09S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| HS Code | 2922498590 | |||||||||
| NFPA 704 |
|
Synephrine hydrochloride price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 5985-28-4 | 10g | $95 | 2024-03-01 | Buy |
| Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 5985-28-4 | 50g | $220 | 2024-03-01 | Buy |
| Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 5985-28-4 | 5g | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 28398 | (±)-Synephrine (hydrochloride) | 5985-28-4 | 25g | $152 | 2024-03-01 | Buy |
| TRC | S920001 | rac-SynephrineHydrochloride | 5985-28-4 | 100g | $410 | 2021-12-16 | Buy |
Synephrine hydrochloride Chemical Properties,Uses,Production
Description
(±)-Synephrine is an alkaloid with vasoconstrictor and metabolic activities. It binds to α1A-, α2A-, and α2C-adrenergic receptors (ARs; Kis = 78, 36.7, and 24.4 μM, respectively). (±)-Synephrine is an agonist of α1A-ARs in HEK293 cells (EC50 = 4 μM in a reporter assay) but not in CHO cells expressing α2A- or α2C-AR. It also acts as an antagonist of α1A-, α2A-, and α2C-ARs, inhibiting L-phenylephrine-induced activation of α1A-AR in HEK293 cells and activation of α2A- and α2C-ARs induced by the α2-AR agonist medetomidine in CHO cells (IC50s = 12.8, 26, and 27.3 μM, respectively, in reporter assays). (±)-Synephrine induces contractions in isolated rabbit aortic rings (EC50 = 6.2 μg/ml) and increases ligation-induced mean arterial pressure in rats when administered at a dose of 2 mg/kg per day. It induces lipolysis in isolated rat and human adipocytes when used at concentrations of 100 and 1,000 μg/ml. (±)-Synephrine (50 μM) increases phosphorylation of Akt and AMP-activated protein kinase (AMPK) and translocation of Glut4 to the plasma membrane, as well as increases insulin-induced glucose consumption in L6 muscle cells when used at concentrations ranging from 25 to 200 μM.
Chemical Properties
Pale Beige Solid
Uses
A α-adrenergic receptor agonist, vasoconstrictor.
Synephrine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 351)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu ChenLv Herb Co.,Ltd | +undefined13608205856 | maryextract@126.com | China | 127 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 311 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 563 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
View Lastest Price from Synephrine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-28 | Synephrine hydrochloride
5985-28-4
|
US $0.00-0.00 / kg | 1kg | 99% | 20t | Jinan Jianfeng Chemical Co., Ltd | |
 |
2024-04-28 | Synephrine hydrochloride
5985-28-4
|
US $0.00 / KG | 1KG | ≥98% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-04-24 | Synephrine HCl
5985-28-4
|
US $120.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- Synephrine hydrochloride
5985-28-4
- US $0.00-0.00 / kg
- 99%
- Jinan Jianfeng Chemical Co., Ltd
-
- Synephrine hydrochloride
5985-28-4
- US $0.00 / KG
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Synephrine HCl
5985-28-4
- US $120.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
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Supply High Quality Synephrine hydrochloride powder CAS NO.:5985-28-4 CAS NO.5985-28-4
Synephrine/Synephrine Hcl
JACS-5985-28-4
Synephrine hydrochloride, 98%, an α-adrenergic and -adrenergic agonist derived from the Citrus aurantium, it has sympathomimetic and structural similarities to ephedra and ephedrine alkaloids
Benzenemethanol, 4-hydroxy-a-[(methylamino)methyl]-, hydrochloride
top quality Synephrine hydrochloride
Synephrine hydrochloride USP/EP/BP
Synephrine hydrochlorid
Pharmaceutical Intermediate CAS?5985-28-4?Synephrine Hydrochloride Synephrine HCl
Synephrine HCl 98%min
5985-28-4
227-804-6
8985-28-4
5983-28-4
85-28-4
C9H14NO2Cl
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5985-28-4