ChemicalBook >> CAS DataBase List >>Chymotrypsin Substrate II, Fluorogenic

Chymotrypsin Substrate II, Fluorogenic

CAS No.
88467-45-2
Chemical Name:
Chymotrypsin Substrate II, Fluorogenic
Synonyms
SUC-AAPF-AMC;FACTOR XIIA SUBSTRATE;Z-LYS-PHE-ARG-PNA 2HCL;SUC-ALA-ALA-PRO-PHE-MCA;SUC-ALA-ALA-PRO-PHE-AMC;Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE;Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC);FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE;CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC;5:PN:WO0197794 SEQID:34 claimed protein
CBNumber:
CB1701335
Molecular Formula:
C34H39N5O9
Molecular Weight:
661.7
MDL Number:
MFCD00080246
MOL File:
88467-45-2.mol
Last updated:2023-11-15 17:26:31

Chymotrypsin Substrate II, Fluorogenic Properties

Boiling point 1093.0±65.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Clear, colorless solution (10 mg/mL in Methanol)
form White lyophilized solid
pka 4.69±0.10(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

Chymotrypsin Substrate II, Fluorogenic price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate 88467-45-2 1mg $94 2024-03-01 Buy
Sigma-Aldrich 230914 Chymotrypsin Substrate II, Fluorogenic 88467-45-2 25mg $142 2024-03-01 Buy
Sigma-Aldrich S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate 88467-45-2 5mg $315 2024-03-01 Buy
TRC C432958 Chymotrypsin Substrate II, Fluorogenic 88467-45-2 50mg $255 2021-12-16 Buy
Chem-Impex 04643 Suc-Ala-Ala-Pro-Phe-AMC,99%(HPLC) 99%(HPLC) 88467-45-2 50MG $436.8 2021-12-16 Buy
Product number Packaging Price Buy
S9761 1mg $94 Buy
230914 25mg $142 Buy
S9761 5mg $315 Buy
C432958 50mg $255 Buy
04643 50MG $436.8 Buy

Chymotrypsin Substrate II, Fluorogenic Chemical Properties,Uses,Production

Description

Chymotrypsin Substrate II, Fluorogenic finds widespread utility across diverse scientific research applications, encompassing the exploration of protein-protein interactions, enzyme kinetics, and receptor binding. Notably, its cost-effectiveness and user-friendly nature render it an appealing choice for researchers. Additionally, this peptide has been instrumental in delving into the intricate world of cell signaling pathways and unraveling the mechanisms governing gene expression regulation. It is postulated to function as a substrate for enzymes while also engaging with receptors. The prevailing belief suggests that the peptide effectively binds to specific receptors, subsequently triggering their activation and instigating consequential alterations in cellular signaling pathways.

Chemical Properties

White powder

Uses

Chymotrypsin Substrate II, Fluorogenic (cas# 88467-45-2) is a useful compound in organic synthesis and acts as a substrate for chymotrypsin enzyme.

Biological Activity

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

References

[1] G B IRVINE C H W M Ennis. Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.[J]. Analytical biochemistry, 1990, 185 2: 304-307. DOI:10.1016/0003-2697(90)90298-n.
[2] LASZLO GRAF. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin[J]. Biochemistry Biochemistry, 1987, 26 9: 2616-2623. DOI:10.1021/bi00383a031.
[3] OSHIMA G. Interaction of alpha-chymotrypsin with dimyristoyl phosphatidylcholine vesicles.[J]. Journal of biochemistry, 1984, 95 4: 1131-1136. DOI:10.1093/oxfordjournals.jbchem.a134701.
[4] OSHIMA G. Stimulation by phospholipid vesicles of proteolysis of egg white lysozyme by chymotrypsin.[J]. Journal of biochemistry, 1983, 5 1: 1615-1620. DOI:10.1093/OXFORDJOURNALS.JBCHEM.A134509.

Chymotrypsin Substrate II, Fluorogenic Preparation Products And Raw materials

Raw materials

Preparation Products

Chymotrypsin Substrate II, Fluorogenic Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696; info@hanhongsci.com China 42982 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80

View Lastest Price from Chymotrypsin Substrate II, Fluorogenic manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE pictures 2022-10-12 FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE
88467-45-2
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-METHYLCOUMARYL-7-AMIDE SUC-AAPF-AMC SUC-ALA-ALA-PRO-PHE-MCA SUC-ALA-ALA-PRO-PHE-7-AMINO-4-METHYLCOUMARIN SUC-ALA-ALA-PRO-PHE-AMC N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-METHYLCOUMARIN Z-LYS-PHE-ARG-PNA 2HCL CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-*ME THYLCOUMARI FACTOR XIIA SUBSTRATE succinylalanylalanyl-prolyl-phenylalanine-4-methylcoumaryl-7-amide Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC) Chymotrypsin Substrate II, Fluorogenic - CAS 88467-45-2 - Calbiochem L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- 5:PN:WO0197794 SEQID:34 claimed protein 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-2-[(4-methyl-2-oxochromen-7-yl)amino]-3-phenylpropanoyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Phenylalaninamide 88467-45-2 C34H39N5O9 Enzymes, Inhibitors, and Substrates Enzyme Substrates Leucine Aminopeptidase Substrates by Enzyme BioChemical Biochemicals and Reagents Chymotrypsin, alphaEnzyme Substrates Leucine aminopeptidase Leucine AminopeptidaseEnzyme Substrates Enzyme Substrates Protease Substrates Substrates by Enzyme