EIPA
- CAS No.
- 1154-25-2
- Chemical Name:
- EIPA
- Synonyms
- ethylisopropylamiloride;EIPA;MH 12-43;L 593754;Ethylisopropylamiloride (EIPA);5-(N-ETHYL-N-ISOPROPYL)AMILORIDE;AMILORIDE, 5-(N-ETHYL-N-ISOPROPYL)-;Amiloride,5-(N-Ethyl-N-isopropyl)-[5-(N-Ethyl-N-isopropyl)amiloride;3-AMino-N-(aMinoiMinoMethyl)-6-chloro-5-[ethyl(1-Methylethyl)aMino]-;3-amino-6-chloro-N-(diaminomethylene)-5-[ethyl(isopropyl)amino]pyrazinamide
- CBNumber:
- CB1706411
- Molecular Formula:
- C11H18ClN7O
- Molecular Weight:
- 299.76
- MDL Number:
- MFCD00151710
- MOL File:
- 1154-25-2.mol
- MSDS File:
- SDS
| Melting point | 202-205 °C(lit.) |
|---|---|
| Density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Acetonitrile (Slightly, Heated), DMSO (Slightly), Methanol (Slightly) |
| pka | 8.67±0.46(Predicted) |
| form | Off-white to yellow solid. |
| color | Pale Yellow to Green |
| Stability | Unstable in methanol |
| CAS DataBase Reference | 1154-25-2 |
| FDA UNII | VW50CE070T |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
EIPA price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A3085 | 5-(N-Ethyl-N-isopropyl)amiloride | 1154-25-2 | 25mg | $233 | 2024-03-01 | Buy |
| Sigma-Aldrich | A3085 | 5-(N-Ethyl-N-isopropyl)amiloride | 1154-25-2 | 100mg | $773 | 2024-03-01 | Buy |
| Cayman Chemical | 14406 | 5-(N-ethyl-N-isopropyl)-Amiloride ≥98% | 1154-25-2 | 5mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 14406 | 5-(N-ethyl-N-isopropyl)-Amiloride ≥98% | 1154-25-2 | 10mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 14406 | 5-(N-ethyl-N-isopropyl)-Amiloride ≥98% | 1154-25-2 | 25mg | $179 | 2024-03-01 | Buy |
EIPA Chemical Properties,Uses,Production
Description
Sodium-
Chemical Properties
Yellow Solid
Uses
5-(N-Ethyl-N-isopropyl)amiloride has been used:
- as a supplement in endothelial cell growth medium to incubate human lung microvascular endothelial cell
- in Pluronic F-127 stock solution for Drosophila larval live-imaging
- in choline chloride solution as an experimental perfusate, to study the effect of Na+/H+ inhibition on jejunal loop perfusion in vivo
Uses
Selective Na+/H+ antiporter inhibitor. Selectively enhances the excretion of sodium ions without causing an increase in excretion of potassium ions.
Definition
ChEBI: Ethylisopropylamiloride is a member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group. It has a role as an anti-arrhythmia drug, a neuroprotective agent and a sodium channel blocker. It is a member of guanidines, an aromatic amine, an organochlorine compound, a tertiary amino compound, a member of pyrazines and a monocarboxylic acid amide. It is functionally related to an amiloride.
Biochem/physiol Actions
Selective blocker of Na+/H+ antiport
storage
Store at +4°C
EIPA Preparation Products And Raw materials
Raw materials
Preparation Products
EIPA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 10026 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
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