CASPASE-3
- CAS No.
- 169592-56-7
- Chemical Name:
- CASPASE-3
- Synonyms
- YAMA;CPP32;CPP321;CASP-3;APOPAIN;CASPASE-3;YAMA HUMAN;CPP32 HUMAN;PROCASPASE-3;APOPAIN HUMAN
- CBNumber:
- CB1710614
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01634593
- MOL File:
- Mol file
| Melting point | 127 °C |
|---|---|
| storage temp. | −70°C |
| solubility | PBS: soluble |
| form | buffered aqueous glycerol solution |
| FDA UNII | 7ZG7Y5NU3G |
CASPASE-3 price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4503294 | Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit affinity isolated antibody | 169592-56-7 | 100μg | $506 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB4503292 | Anti-CSPN3 (Cleaved-Asp175) antibody produced in rabbit affinity isolated antibody | 169592-56-7 | 100μg | $506 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB1305630 | ANTI-CLEAVED-CASP3 (ASP175) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 169592-56-7 | 400μl | $481 | 2024-03-01 | Buy |
| Sigma-Aldrich | 235417 | Caspase-3, Human, Recombinant, E. coli | 169592-56-7 | 5000u | $552 | 2023-01-07 | Buy |
| Usbiological | 354512 | Casp3 | 169592-56-7 | 48Tests | $588 | 2021-12-16 | Buy |
CASPASE-3 Chemical Properties,Uses,Production
Uses
Caspase 3 human has been used to digest human r-vimentin. It has also been used in caspase-3 inhibition assay and protease inhibition assay.
General Description
Human recombinant C-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kDa and 13.5 kDa subunits; the 13.5 kDa subunit contains the histidine tag.
Biochem/physiol Actions
Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase?3 is considered to be an effector caspase, activating pro-caspase?6 and pro-caspase?9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B.
CASPASE-3 Preparation Products And Raw materials
Raw materials
Preparation Products
CASPASE-3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | chenjw@absin.cn | China | 24734 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Sigma-Aldrich | 80 |
| Absin Bioscience Inc. | 58 |
| Shanghai Universal Biotech Co.,Ltd | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 58 |
| United States Biological | 58 |