5-NITROSO-8-HYDROXYQUINOLINE
- CAS No.
- 3565-26-2
- Chemical Name:
- 5-NITROSO-8-HYDROXYQUINOLINE
- Synonyms
- RMH-79;NSC 3852;hydroniii;Hydron III;5-NITROSO-OXINE;5-nitroso-8-quinolino;5-NITROSO-8-QUINOLINOL;5-Nitroso-8-cinnolinol;5-nitrosoquinolin-8-ol;5-Nitrosochinolin-8-ol
- CBNumber:
- CB1711909
- Molecular Formula:
- C9H6N2O2
- Molecular Weight:
- 174.16
- MDL Number:
- MFCD00041862
- MOL File:
- 3565-26-2.mol
- MSDS File:
- SDS
| Melting point | 245 °C |
|---|---|
| Boiling point | 305.12°C (rough estimate) |
| Density | 1.40 |
| refractive index | 1.5651 (estimate) |
| storage temp. | Store at RT |
| solubility | insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL in DMSO |
| form | solid |
| color | Needles from EtOH |
| CAS DataBase Reference | 3565-26-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | P302KW5VDN |
| EPA Substance Registry System | 8-Quinolinol, 5-nitroso- (3565-26-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H319 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 5-40-20/21/22 | |||||||||
| Safety Statements | 36/37 | |||||||||
| Toxicity | mmo-sat 1 mmol/plate MUREAV 164,263,86 | |||||||||
| NFPA 704 |
|
5-NITROSO-8-HYDROXYQUINOLINE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 13856 | 5-Nitroso-8-quinolinol ≥95% | 3565-26-2 | 10mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 13856 | 5-Nitroso-8-quinolinol ≥95% | 3565-26-2 | 50mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 13856 | 5-Nitroso-8-quinolinol ≥95% | 3565-26-2 | 100mg | $213 | 2024-03-01 | Buy |
| Usbiological | 256054 | NSC 3852 | 3565-26-2 | 10mg | $290 | 2021-12-16 | Buy |
| TRC | N546580 | 5-Nitroso-quinolin-8-ol | 3565-26-2 | 100mg | $140 | 2021-12-16 | Buy |
5-NITROSO-8-HYDROXYQUINOLINE Chemical Properties,Uses,Production
Chemical Properties
slightly yellow to yellow-green powder
Uses
5-NITROSO-8-HYDROXYQUINOLINE is shown to have cell differentiation and antiproliferative activity in human breast cancer cells in tissue culture and antitumor activity in mice bearing P388 and L1210 leukemic cells.
Definition
ChEBI: 5-nitroso-8-quinolinol is a hydroxyquinoline.
Biological Activity
Histone deacetylase inhibitor. Causes cell differentiation and antiproliferative activity in MCF-7 human breast cancer cells in vitro and displays antitumor activity in vivo .
Safety Profile
Poison by intravenous and intraperitoneal routes. Many nitroso compounds are carcinogens. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
storage
Room temperature
References
[1]. martirosyan a, leonard s, shi x, et al. actions of a histone deacetylase inhibitor nsc3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in mcf-7 human mammary tumor cells. j pharmacol exp ther, 2006, 317(2): 546-552.
[2]. strobl js, seibert cw, li y, et al. inhibition of toxoplasma gondii and plasmodium falciparum infections in vitro by nsc3852, a redox active antiproliferative and tumor cell differentiation agent. j parasitol, 2009, 95(1): 215-223.
5-NITROSO-8-HYDROXYQUINOLINE Preparation Products And Raw materials
5-NITROSO-8-HYDROXYQUINOLINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
View Lastest Price from 5-NITROSO-8-HYDROXYQUINOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-17 | 5-nitrosoquinolin-8-ol
3565-26-2
|
US $1.00 / KG | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-
- 5-nitrosoquinolin-8-ol
3565-26-2
- US $1.00 / KG
- 98% HPLC
- Career Henan Chemical Co
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