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Dipropylamine structure
Chemical Name:
DPA;DNPA;ai3-24037;(n-C3H7)2NH;DIPROPYLAMINE;Dipropanamine;AURORA KA-7671;N-Dipropylamine;Di-n-propylamin;DI-N-PROPYLAMINE
Molecular Formula:
Formula Weight:
MOL File:

Dipropylamine Properties

Melting point:
-63 °C
Boiling point:
105-110 °C(lit.)
0.738 g/mL at 25 °C(lit.)
vapor pressure 
38 hPa (20 °C)
refractive index 
n20/D 1.4049(lit.)
Flash point:
39 °F
storage temp. 
Flammables area
35g/l (experimental)
pK1:10.91(+1) (25°C)
explosive limit
Water Solubility 
Stable. Highly flammable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
142-84-7(CAS DataBase Reference)
NIST Chemistry Reference
1-Propanamine, n-propyl-(142-84-7)
EPA Substance Registry System
1-Propanamine, N-propyl-(142-84-7)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  F,C
Risk Statements  11-20/21/22-35
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2383 3/PG 2
WGK Germany  1
RTECS  JL9200000
Autoignition Temperature 260 °C
HazardClass  3
PackingGroup  II
HS Code  29211910
Hazardous Substances Data 142-84-7(Hazardous Substances Data)
Toxicity LD50 orally in rats: 0.93 g/kg, H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 23, 95 (1962)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

NFPA 704

Diamond Hazard Value Description
Flammability   3 Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

Dipropylamine price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D214752 Dipropylamine 99% 142-84-7 500ml $30.5 2018-11-13 Buy
Sigma-Aldrich D214752 Dipropylamine 99% 142-84-7 1l $48.6 2018-11-13 Buy
Alfa Aesar L15808 Di-n-propylamine, 99% 142-84-7 500ml $29.3 2018-11-13 Buy
Alfa Aesar L15808 Di-n-propylamine, 99% 142-84-7 100ml $19.7 2018-11-13 Buy
Sigma-Aldrich 8.03548 Dipropylamine for synthesis. CAS 142-84-7, chemical formula (CH CH CH ) NH., for synthesis 142-84-7 8035480100 $26.5 2018-11-23 Buy

Dipropylamine Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Chemical Properties

Dipropylamine, like the other short chain aliphatic amines, is a very strong base, its reactivity being governed by the unshared electron pair on the nitrogen atom. It forms a hydrate with water. The amine also can react with inorganic or organic nitrites under acidic conditions and possibly by reaction with nitrogen oxides from the air to form the highly mutagenic and carcinogenic N-nitrosodipropylamine (ATSDR 1979; Olah et al; Scanlan 1983).

Production Methods

Dipropylamine is manufactured by reaction of propanol and ammonia over a dehydration catalyst at high temperature and pressure (HSDB 1989). Alternatively, propanol and ammonia can be combined with hydrogen over a dehydrogenation catalyst. In each instance, the resulting mixture of primary, secondary, and tertiary amines can be separated by continuous distillation and extraction (Schweizer et al 1978). Dipropylamine is a natural component of vegetables, fish, fruits, and other foods (Mohri 1987) and of tobacco products (WHO 1987). It also is found in human urine (Audunsson 1988), waste water lagoons (Guzewich et al 1983) and in workplace air (Simon and Lemacon 1987).
The toxic compound, N-nitrosodipropylamine, can be produced inadvertently by nitrosation of n-dipropylamine during various manufacturing processes that use the diamine (ATSDR 1989). The nitrosamine, therefore, occurs as an impurity in some dinitroaniline pesticides and rubber products. N-nitrosodipropylamine also is found in various foodstuffs including cheese, cured meats, cooked fish and alcoholic beverages, apparently by reaction of n-dipropylamine with the preservative sodium nitrite (ATSDR 1979; Gross and Newberne 1977; Scanlan 1983).

General Description

A clear colorless liquid with an ammonia-like odor. Flash point 30°F. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Dipropylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation causes severe coughing and chest pain due to irritation of air passages; can-cause lung edema; may also cause headache, nausea, faintness, and anxiety. Ingestion causes irritation and burning of mouth and stomach. Contact with eyes causes severe irritation and edema of the cornea. Contact with skin causes severe irritation.

Health Hazard

Inhalation of dipropylamine vapors can result in severe coughing and chest pain due to irritation of airways. Transient symptoms of exposure may include headache, nausea, faintness, and anxiety. Prolonged breathing of vapors may result in lung edema. Dipropylamine also can cause severe irritation and edema of the cornea. A review of the toxicity of dipropylamine has been prepared (Anon 1987).

Fire Hazard

Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires.

Industrial uses

Dipropylamine is used in the rubber industry and as a chemical intermediate in the manufacture of the herbicides S-ethyl-di-n-propylthiocarbamate and S-propyl di-n-propylthiocarbamate (HSDB 1989). Dipropylamine also is employed in the purification of perfluoro compounds to convert the incompletely fluorinated impurities to solids which are then removed by filtration. In 1984, U.S. production was 41 million pounds.

Safety Profile

Poison by ingestion. Moderately toxic by shin contact and inhalation. A skin irritant. A very dangerous fire hazard, when exposed to heat or flame. Can react with oxidizers. Explosion hazard is unknown. Keep away from heat and open flame. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx,. See also AMINES


There is little information available on the metabolism and disposition of dipropylamine in biological systems. The available evidence suggests that dipropylamine is not a substrate for monoamine oxidase, but rather is inhibitory. Valiev (1974) administered dipropylamine intraperitoneally to rats and reported it to be moderately inhibitory to liver monoamine oxidase. Previous work by this author demonstrated that lethal doses of dipropylamine and other secondary and tertiary amines significantly inhibited rat liver monoamine oxidase activity (Valiev 1968).
The carcinogenic N-nitrosodipropylamine has been detected in the stomach when dipropylamine (present in fish, vegetables and fruit juices) comes in contact with nitrite, which is often used as a food additive in meats and smoked fish (HSDB 1989). Further metabolism of the carcinogen N-nitrosodipropylamine product formed upon nitrosation of dipropylamine is required to form a highly electrophilic carbonium ion capable of alkylating DNA, etc. (Archer 1981).

Dipropylamine Preparation Products And Raw materials

Raw materials

Preparation Products

Dipropylamine Suppliers

Global( 166)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21957 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20676 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32452 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
career henan chemical co
+86-371-86658258 CHINA 25796 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 23957 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20084 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 8267 58
Hubei xin bonus chemical co. LTD
13657299721 CHINA 17424 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76

View Lastest Price from Dipropylamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-11 Dipropylamine
US $1.00 / KG 1KG 99% 25kg career henan chemical co

Dipropylamine Spectrum

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