Ethyl 2-hydroxybenzoate
- CAS No.
- 118-61-6
- Chemical Name:
- Ethyl 2-hydroxybenzoate
- Synonyms
- ETHYL SALICYLATE;Mesotol;Ethyl salicyclate;Salotan;salethyl;Sal Ethyl;Ethyl Liu;FEMA 2458;salicylicether;Ethylsalicylat
- CBNumber:
- CB1723193
- Molecular Formula:
- C9H10O3
- Molecular Weight:
- 166.17
- MDL Number:
- MFCD00002215
- MOL File:
- 118-61-6.mol
- MSDS File:
- SDS
| Melting point | 1 °C (lit.) |
|---|---|
| Boiling point | 234 °C (lit.) |
| Density | 1.131 g/mL at 25 °C (lit.) |
| vapor pressure | 0.05 mm Hg ( 25 °C) |
| refractive index |
n |
| FEMA | 2458 | ETHYL SALICYLATE |
| Flash point | 225 °F |
| storage temp. | Store below +30°C. |
| solubility | 0.25g/l |
| form | Liquid |
| pka | 9.93±0.10(Predicted) |
| color | Clear colorless to pale yellow |
| Odor | at 100.00 %. sweet wintergreen mint floral spicy balsam |
| Odor Type | minty |
| explosive limit | 1.1%(V) |
| Water Solubility | slightly soluble |
| Merck | 14,3850 |
| JECFA Number | 900 |
| BRN | 907659 |
| Dielectric constant | 8.6（21℃） |
| InChIKey | GYCKQBWUSACYIF-UHFFFAOYSA-N |
| LogP | 3.07 at 21.9℃ |
| Substances Added to Food (formerly EAFUS) | ETHYL SALICYLATE |
| FDA 21 CFR | 172.515 |
| CAS DataBase Reference | 118-61-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 555U6TZ2MV |
| NIST Chemistry Reference | Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6) |
| EPA Substance Registry System | Ethyl salicylate (118-61-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/38-52/53 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | VO3000000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29182390 | |||||||||
| Toxicity | LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg | |||||||||
| NFPA 704 |
|
Ethyl 2-hydroxybenzoate price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W245801 | Ethyl salicylate ≥99%, FCC, FG | 118-61-6 | 1kg | $40.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | W245801 | Ethyl salicylate ≥99%, FCC, FG | 118-61-6 | 10Kg | $325 | 2024-03-01 | Buy |
| Sigma-Aldrich | W245801 | Ethyl salicylate ≥99%, FCC, FG | 118-61-6 | 25kg | $699 | 2024-03-01 | Buy |
| Sigma-Aldrich | 112291 | Ethyl salicylate 99% | 118-61-6 | 100g | $28 | 2024-03-01 | Buy |
| Sigma-Aldrich | 112291 | Ethyl salicylate 99% | 118-61-6 | 250g | $55.4 | 2024-03-01 | Buy |
Ethyl 2-hydroxybenzoate Chemical Properties,Uses,Production
Description
Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents.
Chemical Properties
Ethyl salicylate has a characteristic aromatic odor similar to wintergreen. It tends to darken on exposure to light and air.
Chemical Properties
Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. It has a pleasant odor resembling winter green and is used in perfumery and artificial flavors.
Chemical Properties
clear colourless to pale yellow liquid
Occurrence
Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa fruit, papaya and scotch.
Uses
Ethyl salicylate may be used as an analytical standard for the determination of the analyte in biological fluids and topical formulation by chromatography-based techniques.
Uses
Ethyl salicylate is a non-steroidal analgesic, anti-inflammatory and antirrheumatic drug. Its complexation with β-cyclodextrin was studied using reversed-phase liquid chromatography.
Uses
manufacture of artificial perfumes.
Production Methods
Ethyl salicylate is found naturally in currants and strawberries . It is manufactured commercially by the esterification of salicylic acid with ethyl alcohol.
Definition
ChEBI: Ethyl salicylate is a hydroxybenzoic acid.
Preparation
By esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.
Taste threshold values
Taste characteristics at 10 ppm: sweet, wintergreen, spicy and anisic.
General Description
Ethyl salicylate was hydrolysed to salicylic acid by the use of an extractive electrospray ionisation (EESI) device.
Flammability and Explosibility
Not classified
References
Sheu, Yaw-Wen, and Chein-Hsiun Tu. "Densities and viscosities of binary mixtures of ethyl acetoacetate, ethyl isovalerate, methyl benzoate, benzyl acetate, ethyl salicylate, and benzyl propionate with ethanol at T=(288.15, 298.15, 308.15, and 318.15) K." Journal of Chemical & Engineering Data 51.2 (2006): 545-553.
Filippa, Mauricio, Matías I. Sancho, and Estela Gasull. "Encapsulation of methyl and ethyl salicylates by β-cyclodextrin: HPLC, UV–vis and molecular modeling studies." Journal of pharmaceutical and biomedical analysis 48.3 (2008): 969-973.
Ethyl 2-hydroxybenzoate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd | 510-85010237 | overseamarketing@alphahi-tech.com | CHINA | 41 | 58 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
View Lastest Price from Ethyl 2-hydroxybenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-07 | ethyl 2-hydroxybenzoate
118-61-6
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. | |
 |
2023-08-16 | Ethyl salicylate
118-61-6
|
US $175.00 / KG | 1KG | >99% | 50000kg/Month | Weijer International Trade (Hebei) Co., Ltd | |
 |
2023-05-28 | Ethyl 2-hydroxybenzoate
118-61-6
|
US $0.00-0.00 / kg | 1kg | 0.99 | 500000kg | Hebei Yibangte Import and Export Co. , Ltd. |
-
- ethyl 2-hydroxybenzoate
118-61-6
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
-
- Ethyl salicylate
118-61-6
- US $175.00 / KG
- >99%
- Weijer International Trade (Hebei) Co., Ltd
-
- Ethyl 2-hydroxybenzoate
118-61-6
- US $0.00-0.00 / kg
- 0.99
- Hebei Yibangte Import and Export Co. , Ltd.