ChemicalBook >> CAS DataBase List >>2,4-Dichloro-1,3,5-triazine

2,4-Dichloro-1,3,5-triazine

CAS No.
2831-66-5
Chemical Name:
2,4-Dichloro-1,3,5-triazine
Synonyms
oro-1,3,5-triazine;Dichloro-s-triazine;2,4-dichlorotriazine;2,4-Dichloro-s-triazine;2,4-DICHLORO-1,3,5-TRIAZINE;1,3,5-Triazine,2,4-dichloro-;2,4-Dichloro-1,3,5-triazine>2,4-Dichloro-1,3,5-Triazine pure, 98%
CBNumber:
CB1748811
Molecular Formula:
C3HCl2N3
Molecular Weight:
149.97
MDL Number:
MFCD04115347
MOL File:
2831-66-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:00
Product description Number Pack Size Price
2,4-Dichloro-1,3,5-triazine >98.0%(GC)(T) D4891 1g $43
2,4-Dichloro-1,3,5-triazine >98.0%(GC)(T) D4891 5g $144
2,4-DICHLORO-1,3,5-TRIAZINE 95% 68422 1G $25
2,4-DICHLORO-1,3,5-TRIAZINE 95% 68422 5G $49
2,4-DICHLORO-1,3,5-TRIAZINE 95% 68422 25G $148
More product size

2,4-Dichloro-1,3,5-triazine Properties

Melting point 54.0 to 58.0 °C
Boiling point 102°C/75mmHg(lit.)
Density 1.612±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka -1.24±0.10(Predicted)
color White to Off-White
InChI InChI=1S/C3HCl2N3/c4-2-6-1-7-3(5)8-2/h1H
InChIKey OMRXVBREYFZQHU-UHFFFAOYSA-N
SMILES N1=CN=C(Cl)N=C1Cl
CAS DataBase Reference 2831-66-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  2933698090

2,4-Dichloro-1,3,5-triazine price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D4891 2,4-Dichloro-1,3,5-triazine >98.0%(GC)(T) 2831-66-5 1g $43 2026-04-30 Buy
TCI Chemical D4891 2,4-Dichloro-1,3,5-triazine >98.0%(GC)(T) 2831-66-5 5g $144 2026-04-30 Buy
AstaTech 68422 2,4-DICHLORO-1,3,5-TRIAZINE 95% 2831-66-5 1G $25 2026-04-30 Buy
AstaTech 68422 2,4-DICHLORO-1,3,5-TRIAZINE 95% 2831-66-5 5G $49 2026-04-30 Buy
AstaTech 68422 2,4-DICHLORO-1,3,5-TRIAZINE 95% 2831-66-5 25G $148 2026-04-30 Buy
Product number Packaging Price Buy
D4891 1g $43 Buy
D4891 5g $144 Buy
68422 1G $25 Buy
68422 5G $49 Buy
68422 25G $148 Buy

2,4-Dichloro-1,3,5-triazine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

2,4-Dichloro-1,3,5-triazine is used as an intermediate in organic synthesis and pharmaceutical intermediates, and it is an intermediate in the preparation of bromhexine impurities.

Preparation

2,4-Dichloro-1,3,5-triazine can be synthesized by halogenation of 1,3,5-Triazine with chlorine.

Synthesis

Sodium dicyanamide

1934-75-4

N,N-Dimethylformamide

68-12-2

2,4-Dichloro-1,3,5-triazine

2831-66-5

General procedure for the synthesis of 2,4-dichloro-1,3,5-triazine from sodium dicyandiamide and N,N-dimethylformamide: Sodium dicyandiamide (3.0 g, 33.70 mmol) was dissolved in water (13 ml) and the solution was transferred to a flask containing concentrated hydrochloric acid. Hydrochloric acid (15 ml) was added slowly at -78°C. The reaction mixture was stirred at -78°C for 15 min, followed by warming to -35°C and continued stirring for 15 min. After that, the mixture was cooled to 0 °C and the precipitate was collected by filtration. Another flask containing N,N-dimethylformamide (10 ml) was prepared at room temperature to which phosphorous trichloride (1.84 ml, 19.71 mmol) and N,N-dimethylformamide (1.53 ml, 19.71 mmol) were added dropwise at 0 °C. After brief stirring, the resulting mixture was added to the above precipitate in batches, followed by stirring at room temperature overnight. After completion of the reaction, the reaction was quenched with water and the mixture was extracted with ethyl acetate (30 ml x 3). The residue was purified by silica gel fast column chromatography (eluent: ethyl acetate/hexane=1:4, Rf=0.63) to afford 2,4-dichloro-1,3,5-triazine (0.64 g, yield 13.13%) as a white solid.1H-NMR (300 MHz, CDCl3): δ 8.90 (s, 1H).

References

[1] Patent: WO2017/15400, 2017, A1. Location in patent: Paragraph 0044; 0058

290-87-9
2831-66-5
108-77-0
Synthesis of 2,4-Dichloro-1,3,5-triazine from 1,3,5-Triazine
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View Lastest Price from 2,4-Dichloro-1,3,5-triazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dichloro-1,3,5-triazine pictures 2025-04-04 2,4-Dichloro-1,3,5-triazine
2831-66-5
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
 2,4-DICHLORO-1,3,5-TRIAZINE pictures 2019-07-06 2,4-DICHLORO-1,3,5-TRIAZINE
2831-66-5
US $8.00 / kg 1kg 99% 10TON Career Henan Chemical Co
2,4-DICHLORO-1,3,5-TRIAZINE 2,4-dichlorotriazine 2,4-Dichloro-s-triazine 1,3,5-Triazine,2,4-dichloro- 2,4-Dichloro-1,3,5-triazine> oro-1,3,5-triazine 2,4-Dichloro-1,3,5-Triazine pure, 98% Dichloro-s-triazine 2831-66-5 831-66-5 C3HCl2N3 alkyl chloride Heterocycles