Metrizoic acid
- CAS No.
- 1949-45-7
- Chemical Name:
- Metrizoic acid
- Synonyms
- Metrizoic;metrizoate;Triosil-280;METRIZOIC ACID;MetrizoicAcid>Metrizoic acid USP/EP/BP;3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido);3,5-DiacetaMido-N-Methyl-2,4,6-triiodobenzoic Acid;3-acetamido-2,4,6-triiodo-5-N-methylacetamidobenzoic acid;3-acetamido-2,4,6-triiodo-5-(n-methylacetamido)-benzoicaci
- CBNumber:
- CB1775662
- Molecular Formula:
- C12H11I3N2O4
- Molecular Weight:
- 627.94
- MDL Number:
- MFCD00867964
- MOL File:
- 1949-45-7.mol
- MSDS File:
- SDS
| Melting point | 281-282° |
|---|---|
| Boiling point | 678.8±55.0 °C(Predicted) |
| Density | 2.3140 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMSO |
| form | Solid |
| pka | 0.82±0.10(Predicted) |
| color | White |
| Merck | 14,6156 |
| CAS DataBase Reference | 1949-45-7(CAS DataBase Reference) |
| FDA UNII | CM1N99QR1M |
| ATC code | V08AA02 |
| EPA Substance Registry System | Benzoic acid, 3-(acetylamino)-5-(acetylmethylamino)-2,4,6-triiodo- (1949-45-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| RTECS | DG0887300 |
| HS Code | 2924.29.7790 |
Metrizoic acid price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M1363 | Metrizoic Acid >98.0%(T)(HPLC) | 1949-45-7 | 5g | $31 | 2024-03-01 | Buy |
| TCI Chemical | M1363 | Metrizoic Acid >98.0%(T)(HPLC) | 1949-45-7 | 25g | $59 | 2024-03-01 | Buy |
| TRC | M338935 | Metrizoic Acid | 1949-45-7 | 10g | $950 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 41633 | Metrizoic Acid | 1949-45-7 | 10g | $1460 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0030393 | METRIZOIC ACID 95.00% | 1949-45-7 | 10G | $2148.3 | 2021-12-16 | Buy |
Metrizoic acid Chemical Properties,Uses,Production
Originator
Isopaque,Winthrop,France,1973
Uses
Diagnosis aid (radiopaque medium).
Definition
ChEBI: Metrizoic acid is a monocarboxylic acid. It has a role as a radioopaque medium.
Manufacturing Process
3,5-Diacetamido-2,4,6-triiodobenzoic acid (diatrizoic acid) (see Diatrizoate entry for synthesis) (10 g) is suspended in water (10 ml), 5 N potassium hydroxide (4.3 equivalent) is added and the mixture cooled to about 15°C. Dimethyl sulfate (0.5 equivalent) dissolved in an equal volume of acetone is added drop by drop while stirring. After the reaction mixture has been stirred for about 1 hour hydrochloric acid (1:1) is added, with stirring to pH about 0.5. The precipitate is filtered, washed and suspended moist in 4 parts of water, concentrated ammonia is added to pH about 7 and the ammonium salt solution is isomerized at 90°C to 100°C for about one-half hour whereafter additional ammonia is added to pH about 9 followed by solid ammonium chloride (about 10% weight/volume) and the solution stirred overnight and the excess of 3,5-diacetamide-2,4,6-triiodobenzoic acid recovered as ammonium salt on the filter. The filtrate is precipitated by means of hydrochloric acid (1:1 ) at pH about 0.5 and the N-methyl-3,5-diacetamido- 2,4,6-triiodobenzoic acid collected on a filter, washed and dried.
Therapeutic Function
Diagnostic aid (radiopaque medium)
Metrizoic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9320 | 58 |
| Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 | erin@hbldbiotech.com | China | 878 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18456 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
View Lastest Price from Metrizoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-10-20 | Metrizoic acid
1949-45-7
|
US $350.00 / KG | 1KG | 99% | 9000kg/per week | Hebei Lingding Biotechnology Co., Ltd. | |
 |
2021-08-14 | Metrizoic acid USP/EP/BP
1949-45-7
|
US $1.10 / g | 1g | 0.999 | 100 Tons min | Dideu Industries Group Limited |
-
- Metrizoic acid
1949-45-7
- US $350.00 / KG
- 99%
- Hebei Lingding Biotechnology Co., Ltd.
-
- Metrizoic acid USP/EP/BP
1949-45-7
- US $1.10 / g
- 0.999
- Dideu Industries Group Limited
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