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ChemicalBook >> CAS DataBase List >>4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Structure
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE structure
CAS No.
14279-91-5
Chemical Name:
4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE
Synonyms
BW 65-100 (hydrochloride);4-ChlorophenylguanidineHCl;(4-Chlorophenyl)guanidine Hydrochlo;p-Chlorophenylguanidine Hydrochloride;4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE;Chlorhexidine Digluconate EP Impurity E;1-(4-chlorophenyl)guanidine hydrochloride;Chlorhexidine Diacetate EP Impurity E as Hydrochloride;4 Chlorophenylguanidine hydrochloride,4Chlorophenylguanidine hydrochloride
CBNumber:
CB1779701
Molecular Formula:
C7H9Cl2N3
Molecular Weight:
206.07
MDL Number:
MFCD00209839
MOL File:
14279-91-5.mol
Last updated:2023-06-30 15:45:59
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4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Properties

Melting point 237-238 °C(Solv: water (7732-18-5))
storage temp. Store at RT
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Pale Green
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 0442 4-Chlorophenylguanidinehydrochloride ≥98%(HPLC) 14279-91-5 100 $210 2021-12-16 Buy
Usbiological 254406 4-Chlorophenylguanidine hydrochloride 14279-91-5 100mg $495 2021-12-16 Buy
TRC C377740 p-​Chlorophenylguanidin​eHydrochloride 14279-91-5 25mg $130 2021-12-16 Buy
American Custom Chemicals Corporation NUC0002752 4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE 95.00% 14279-91-5 5MG $497.99 2021-12-16 Buy
Labseeker SC-60354 4-CHLOROPHENYLGUANIDINEHYDROCHLORIDE 95 14279-91-5 10g $2475 2021-12-16 Buy
Product number Packaging Price Buy
0442 100 $210 Buy
254406 100mg $495 Buy
C377740 25mg $130 Buy
NUC0002752 5MG $497.99 Buy
SC-60354 10g $2475 Buy

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

p-Chlorophenylguanidine Hydrochloride is an reagent used in the synthesis of pyrimidine derivatives as hSMG-1 inhibitors, potential targets for cancer treatment.

Biological Activity

4-chlorophenylguanidine hydrochloride is a potent and selective inhibitor of urokinase [1].urokinase is a serine protease. its primary physiological substrate is plasminogen, which is an inactive form of plasmin. urokinase plays an important role in vascular diseases and cancer.4-chlorophenylguanidine hydrochloride inhibited urokinase and trypsin with ki value of 6.07 μm and 120 μm, respectively [1].

storage

Store at RT

References

[1]. yang h, henkin j, kim kh, et al. selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. j med chem, 1990, 33(11): 2956-2961.

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-83725681-603 China 4505 50
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 SALES@UHNSHANGHAI.COM China 977 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2784 58
ShangHai Wisacheam Pharmaceutical Co., Ltd. 13817485796 tim@wisacheampharm.com China 3676 58
JW & Y Pharmlab Co., Ltd. 021-64340559 13651849907; xinyu_shi@jwypharmlab.com.cn China 12042 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Aikon International Limited 025-66113011 13155353615 qzhang@aikonchem.com China 15396 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
UHN Shanghai Research & Development Co., Ltd. 58
AdooQ BioScience, LLC 58
ShangHai Wisacheam Pharmaceutical Co., Ltd. 58
JW & Y Pharmlab Co., Ltd. 58
EMMX Biotechnology LLC 60
Aikon International Limited 58

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4-CHLOROPHENYLGUANIDINE HYDROCHLORIDE 4-ChlorophenylguanidineHCl p-Chlorophenylguanidine Hydrochloride Chlorhexidine Digluconate EP Impurity E (4-Chlorophenyl)guanidine Hydrochlo 1-(4-chlorophenyl)guanidine hydrochloride BW 65-100 (hydrochloride) 4 Chlorophenylguanidine hydrochloride,4Chlorophenylguanidine hydrochloride Chlorhexidine Diacetate EP Impurity E as Hydrochloride 14279-91-5 C7H9Cl2N3 C7H8CIN3HCl