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Imidapril

Imidapril structure

CAS No.: 89371-37-9

Chemical Name:: Imidapril

Synonyms: IMIDAPRIL;lmidaprfil;Imidapril HCl;Imidapril Hyd;Imidapril-d5 HCl;(S,S,S)-Imidapril;Imidapril USP/EP/BP;IMidapril (Tanatril);(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid;(4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid

CBNumber:: CB1780943

Molecular Formula:: C20H27N3O6

Molecular Weight:: 405.44

MDL Number:: MFCD00870777

MOL File:: 89371-37-9.mol

Last updated:2023-05-04 17:34:43

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Imidapril Properties

Melting point	195-197°C
alpha	D20 -71.7° (c = 0.5 in ethanol)
Boiling point	577.0±60.0 °C(Predicted)
Density	1.266±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
pka	2.44±0.20(Predicted)
CAS DataBase Reference	89371-37-9(CAS DataBase Reference)
FDA UNII	BW7H1TJS22
ATC code	C09AA16

Imidapril price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0006470	IMIDAPRIL 95.00%	89371-37-9	10MG	$191.1	2021-12-16	Buy
American Custom Chemicals Corporation	API0006470	IMIDAPRIL 95.00%	89371-37-9	100MG	$1593.9	2021-12-16	Buy
Medical Isotopes, Inc.	11104	ImidaprilHCl	89371-37-9	50mg	$1880	2021-12-16	Buy
AvaChem	1689B	Imidapril	89371-37-9	10mg	$59	2021-12-16	Buy
AvaChem	1689B	Imidapril	89371-37-9	25mg	$119	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0006470	10MG	$191.1	Buy
API0006470	100MG	$1593.9	Buy
11104	50mg	$1880	Buy
1689B	10mg	$59	Buy
1689B	25mg	$119	Buy

Imidapril Chemical Properties,Uses,Production

Description

Imidapril is a new ACE inhibitor launched in Japan as a once-daily therapy for hypertension. Its active metabolite has more potent inhibitory effects on all tissue ACES from spontaneously hypertensive rats (SHRs) and Wistar Kyoto rats (WKYs) than many other ACE inhibitors including enalapril and captopril. It has a very long duration of action. In strokeprone spontaneously hypertensive rats (SHRSP), imidapril is effective in stroke prevention at a considerably lower dose than enalapril. This stroke preventive effect has been suggested to be primarily by an indirect mechanism related to the amelioration of kidney dysfunction.

Chemical Properties

White Solid

Originator

Tanabe (Japan)

Uses

Angiotensin converting enzyme (ACE) inhibitor. Antihypertensive

Definition

ChEBI: Imidapril is a member of the class of imidazolidines that is (4S)-1-methyl-2-oxoimidazolidine-4-carboxylic acid in which the hydrogen of the imidazolidine nitrogen has been substituted by (1S)-1-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}ethyl group. It is the prodrug for imidaprilat, an ACE inhibitor used for the treatment of chronic heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It is a dipeptide, a member of imidazolidines, a dicarboxylic acid monoester, a secondary amino compound, an ethyl ester and a N-acylurea.

brand name

Tanatril; Novarok

Imidapril Preparation Products And Raw materials

Raw materials

N-Hydroxysuccinimide Potassium tert-butoxide Ethyl butyrate Benzyl ester 4-Phenylbutyric acid

Propionyl chloride Midazopril hydrochloride 1-Methylpyrazole-4-ethoxycarbonyl-5-ethoxycarbonylsulfonamide Bromobenzene Imidazolidine

Aniline D-Alanine Tert-butyl ester Iodomethane (2S)-1-(3-Acetylthio-2-methyl-1-oxopropyl)-L-proline

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Preparation Products

Imidapril Suppliers

Global( 114)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9320	58
Hebei Lingding Biotechnology Co., Ltd.	+86-18031140164 +86-19933155420	erin@hbldbiotech.com	China	878	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850 +86-13986145403	info@fortunachem.com	China	5988	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	992	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Lingding Biotechnology Co., Ltd.	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
Wuhan Fortuna Chemical Co., Ltd	58
Sinoway Industrial co., ltd.	58

View Lastest Price from Imidapril manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-10-20	Imidapril 89371-37-9	US $15.00 / KG	1KG	99%	9000kg/per week	Hebei Lingding Biotechnology Co., Ltd.
2021-10-19	Imidapril Hydrochloride 89371-37-9	US $0.00-0.00 / Kg/Drum	1KG	99%min	500kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2021-08-11	Imidapril USP/EP/BP 89371-37-9	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited

Imidapril
89371-37-9
US $15.00 / KG
99%
Hebei Lingding Biotechnology Co., Ltd.

Imidapril Hydrochloride
89371-37-9
US $0.00-0.00 / Kg/Drum
99%min
WUHAN FORTUNA CHEMICAL CO., LTD

Imidapril USP/EP/BP
89371-37-9
US $1.10 / g
99.9%
Dideu Industries Group Limited

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(s)-3-(n-((s)-1-ethoxycarbonyl-3-phenylpropyl)-l-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid IMIDAPRIL (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Aci 4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, (4S)- 4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, [4S-[3[R*(R*)],4R*]]- (4S)-3-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic Acid Hydrochloride (4S)-3-[(2S)-2-[N-[(1S)-1-(Ethyoxycarbonyl)-3-phenylpropyl]amino]propionyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid lmidaprfil (4S)-3-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]propionyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid (4S)-3-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid (S,S,S)-Imidapril Imidapril HCl IMidapril (Tanatril) Imidapril-d5 HCl Imidapril USP/EP/BP Imidapril Hyd 89371-37-9 9371-37-9 C20H27N3O6 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals