ChemicalBook >> CAS DataBase List >>MRGPRX1 agonist 1
MRGPRX1 agonist 1
- CAS No.
- 2377379-39-8
- Chemical Name:
- MRGPRX1 agonist 1
- Synonyms
- BUN79398;MRGPRX1 agonist 1;MRGPRX1 agonist 1,Inhibitor,MRGPRX-1 agonist 1,inhibit;Benzenesulfonamide, N-[2-[(1-amino-6-isoquinolinyl)oxy]-4-methylphenyl]-2-methoxy-
- CBNumber:
- CB18054464
- Molecular Formula:
- C23H21N3O4S
- Molecular Weight:
- 435.5
- MDL Number:
- MFCD32263428
- MOL File:
- 2377379-39-8.mol
Last updated:2023-11-24 16:35:06
| Boiling point | 642.0±65.0 °C(Predicted) |
|---|---|
| Density | 1.365±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : 130 mg/mL (298.51 mM; Need ultrasonic) |
| pka | 8.81±0.10(Predicted) |
| InChI | InChI=1S/C23H21N3O4S/c1-15-7-10-19(26-31(27,28)22-6-4-3-5-20(22)29-2)21(13-15)30-17-8-9-18-16(14-17)11-12-25-23(18)24/h3-14,26H,1-2H3,(H2,24,25) |
| InChIKey | BWEJNHRMGZUMNU-UHFFFAOYSA-N |
| SMILES | C1(S(NC2=CC=C(C)C=C2OC2C=CC3=C(C=2)C=CN=C3N)(=O)=O)=CC=CC=C1OC |
MRGPRX1 agonist 1 Chemical Properties,Uses,Production
Biological Activity
MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].
References
[1]. Prchalová E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641.
MRGPRX1 agonist 1 Preparation Products And Raw materials
Raw materials
Preparation Products
MRGPRX1 agonist 1 Suppliers
Global( 24)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4398 | 58 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8012 | 62 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2985 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9747 | 58 |
MRGPRX1 agonist 1
MRGPRX1 agonist 1,Inhibitor,MRGPRX-1 agonist 1,inhibit
Benzenesulfonamide, N-[2-[(1-amino-6-isoquinolinyl)oxy]-4-methylphenyl]-2-methoxy-
BUN79398
2377379-39-8