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Phthalimide-PEG3-C2-OTs

CAS No.
382162-12-1
Chemical Name:
Phthalimide-PEG3-C2-OTs
Synonyms
Phthalimide-PEG3-C2-OTs;1H-Isoindole-1,3(2H)-dione, 2-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]-
CBNumber:
CB18054792
Molecular Formula:
C23H27NO8S
Molecular Weight:
477.53
MDL Number:
MFCD29079274
MOL File:
382162-12-1.mol
Last updated:2023-02-23 14:24:01

Phthalimide-PEG3-C2-OTs Properties

Boiling point 624.4±55.0 °C(Predicted)
Density 1.300±0.06 g/cm3(Predicted)
pka -2.26±0.20(Predicted)

Phthalimide-PEG3-C2-OTs price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
A1 Biochem Labs 6565435 2-(2-(2-(2-(1,3-Dioxoisoindolin-2-yl)ethoxy)ethoxy)ethoxy)ethyl4-methylbenzenesulfonate 95% 382162-12-1 1g $850 2021-12-16 Buy
Product number Packaging Price Buy
6565435 1g $850 Buy

Phthalimide-PEG3-C2-OTs Chemical Properties,Uses,Production

Biological Activity

Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG3-C2-OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Stegmaier P, et al. Photoactive branched and linear surface architectures for functional and patterned immobilization of proteins and cells onto surfaces: a comparative study. Chemphyschem. 2009 Feb 2;10(2):357-69.

Phthalimide-PEG3-C2-OTs Preparation Products And Raw materials

Raw materials

Preparation Products

Phthalimide-PEG3-C2-OTs Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Phthalimide-PEG3-C2-OTs 1H-Isoindole-1,3(2H)-dione, 2-[2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]ethyl]- 382162-12-1