ChemicalBook >> CAS DataBase List >>Trastuzumab Deruxtecan
Trastuzumab Deruxtecan
- CAS No.
- 1826843-81-5
- Chemical Name:
- Trastuzumab Deruxtecan
- Synonyms
- Enhertu;Trastuzumab Deruxtecan;Fam-trastuzumab deruxtecan;Trastuzumab deruxtecan (solution);DS-8201a|||VRN-101099|||DS 8201|||T-DXd
- CBNumber:
- CB18081028
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2024-10-31 18:15:48
| storage temp. | Solution, -20°C, 2 years |
|---|---|
| solubility | Soluble in acetonitrile |
| form | Solid |
| color | White to off-white |
| FDA UNII | 5384HK7574 |
| ATC code | L01XC41 |
Trastuzumab Deruxtecan Chemical Properties,Uses,Production
Biological Activity
Trastuzumab deruxtecan (DS-8201a) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC).
in vitro
Trastuzumab deruxtecan (1 pM-10 nM; 5 days) inhibits the growth of HER2‐positive KPL‐4 cells, with an IC 50 of 109.7 pM.
Trastuzumab deruxtecan (10 nM; 5 days) shows bystander killing effects in HER2‐negative MDA‐MB‐468 cells.
in vivo
Trastuzumab deruxtecan (3 mg/kg; a single iv) shows antitumor activity against not only HER2‐positive tumors but also HER2‐negative tumors under the co‐inoculated condition.
Trastuzumab Deruxtecan Preparation Products And Raw materials
Raw materials
Preparation Products
Trastuzumab Deruxtecan Suppliers
Global( 24)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32024 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 3059 | 58 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 | sales@sunlidabio.com | China | 3239 | 55 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3466 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10351 | 58 |
| Shanghai Minkai Biological Technology Co., Ltd | 021-021-52919136 17315815539 | 2804155403@qq.com | China | 205 | 58 |
| Jiangxi ravel Biotechnology Co.,Ltd | 400-880-2824 18107960669 | 79046690@qq.com | China | 1267 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
Related articles
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- The introduction of Trastuzumab Deruxtecan
- Trastuzumab deruxtecan, a HER2-directed antibody and DNA topoisomerase I inhibitor conjugate, is being developed for the treat....
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View Lastest Price from Trastuzumab Deruxtecan manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-31 | Trastuzumab deruxtecan
1826843-81-5
|
US $728.00-1960.00 / mg | SEC-HPLC:98.49% | 10g | TargetMol Chemicals Inc. |
-
- Trastuzumab deruxtecan
1826843-81-5
- US $728.00-1960.00 / mg
- SEC-HPLC:98.49%
- TargetMol Chemicals Inc.
Trastuzumab Deruxtecan
Trastuzumab deruxtecan (solution)
Fam-trastuzumab deruxtecan
DS-8201a|||VRN-101099|||DS 8201|||T-DXd
Enhertu
1826843-81-5