ChemicalBook >> CAS DataBase List >>Trastuzumab Deruxtecan
Trastuzumab Deruxtecan
- CAS No.
- 1826843-81-5
- Chemical Name:
- Trastuzumab Deruxtecan
- Synonyms
- Trastuzumab Deruxtecan;Fam-trastuzumab deruxtecan;Trastuzumab deruxtecan (solution)
- CBNumber:
- CB18081028
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2024-02-04 15:10:23
| storage temp. | Solution, -20°C, 2 years |
|---|---|
| solubility | Soluble in acetonitrile |
| FDA UNII | 5384HK7574 |
| ATC code | L01XC41 |
Trastuzumab Deruxtecan Chemical Properties,Uses,Production
Biological Activity
Trastuzumab deruxtecan (DS-8201a) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC).
in vitro
Trastuzumab deruxtecan (1 pM-10 nM; 5 days) inhibits the growth of HER2‐positive KPL‐4 cells, with an IC 50 of 109.7 pM.
Trastuzumab deruxtecan (10 nM; 5 days) shows bystander killing effects in HER2‐negative MDA‐MB‐468 cells.
in vivo
Trastuzumab deruxtecan (3 mg/kg; a single iv) shows antitumor activity against not only HER2‐positive tumors but also HER2‐negative tumors under the co‐inoculated condition.
Trastuzumab Deruxtecan Preparation Products And Raw materials
Raw materials
Preparation Products
Trastuzumab Deruxtecan Suppliers
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4664 | 58 |
| Wuhan Acumen Bio-Technology Co.,ltd | 027-027-16602739303 16602739303 | 673003916@qq.com | China | 2942 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3423 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10055 | 58 |
| Shanghai Minkai Biological Technology Co., Ltd | 021-52919136 17315815539 | 2804155403@qq.com | China | 169 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
| Jiangxi ravel Biotechnology Co.,Ltd | 400-880-2824 15608648206 | 1987516016@qq.com | China | 2608 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 13720134139 | orders@jknbiochem.com | China | 5278 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | cb5@aikonchem.com | China | 10529 | 58 |
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Trastuzumab Deruxtecan
Trastuzumab deruxtecan (solution)
Fam-trastuzumab deruxtecan
1826843-81-5