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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate structure

CAS No.: 206184-49-8

Chemical Name:: 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate

Synonyms: Tenofovir CRS;Tenofovir(H2O);Unii-99yxe507il;PMPA Monohydrate;Tenofovir (15 mg);Tenofovir (hydrate);R-PMPA of Tenofovir;Tenofovir (1643601);Tenofovir Monohydrate;Tenofovir hydrate (GS 1278)

CBNumber:: CB1855342

Molecular Formula:: C9H16N5O5P

Molecular Weight:: 305.23

MDL Number:: MFCD11519982

MOL File:: 206184-49-8.mol

MSDS File:: SDS

Last updated:2023-07-12 18:09:44

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9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Properties

Melting point	270-274oC
storage temp.	2-8°C
solubility	Aqueous Acid (Slightly), DMSO (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic
FDA UNII	99YXE507IL

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301+P330+P331+P310
HS Code	2933599550

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR1592	Tenofovir Pharmaceutical Secondary Standard; Certified Reference Material	206184-49-8	1G	$160	2022-05-15	Buy
Sigma-Aldrich	1643601	Tenofovir United States Pharmacopeia (USP) Reference Standard	206184-49-8	15MG	$400	2022-05-15	Buy
TRC	T185533	TenofovirMonohydrate	206184-49-8	2.5g	$145	2021-12-16	Buy
ChemScene	CS-1874	Tenofovir Hydrate ≥98.0%	206184-49-8	5mg	$50	2021-12-16	Buy
ApexBio Technology	B1252	Tenofovir Hydrate	206184-49-8	50mg	$221	2021-12-16	Buy

Product number	Packaging	Price	Buy
PHR1592	1G	$160	Buy
1643601	15MG	$400	Buy
T185533	2.5g	$145	Buy
CS-1874	5mg	$50	Buy
B1252	50mg	$221	Buy

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Chemical Properties,Uses,Production

Chemical Properties

WHITE POWDER SOLID

Uses

antineoplastic, thymidylate synthase inhibitor

Uses

Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.

Definition

ChEBI: A hydrate that is the monohydrate form of anhydrous tenovir.

General Description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tenofovir is a nucleotide analog reverse transcriptase inhibitor, and is widely used as an antiretroviral agent, for the treatment of HIV infection.

Biological Activity

tenofovir hydrate is an inhibitor of reverse transcriptase used for the treatment of the human immunodeficiency virus 1(hiv-1) and hepatitis b [1].tenofovir hydrate is an antiviral pro-drug and the class of nucleoside reverse transcriptase inhibitor. in addition, tenofovir hydrate has been reported to have a dependent relation between intracellular the drug concentrations and prevent function of hiv-1infection with ec50 values of 29 fmol/106, 40 fmol/106 , 77 fmol/106 and 411 fmol/106 cells for inoculum size 1, 5, 20 and 100 respectively. and the ec90 values of tenofovir hydrate are 267 fmol/106, 348 fmol/106, 640 fmol/106 and 2866 fmol/106 cells for virus inoculums size 1, 5, 20 and 100, respectively [1].

References

[1] duwal s1, schütte c, von kleist m.pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against hiv-1 infection. plos one. 2012;7(7):e40382. doi: 10.1371/journal.pone.0040382. epub 2012 jul 11.

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Suppliers

Global( 155)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou ICH Biofarm Co., Ltd	+undefined8613073685410	sales@ichemie.com	China	985	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Huaian yishu technology co.,ltd	86-0517-85883738 13852390259	sales@yishuchem.com	CHINA	53	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21149	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58

Supplier	Advantage
Hangzhou ICH Biofarm Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Huaian yishu technology co.,ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

View Lastest Price from 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-11-01	9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate 206184-49-8	US $0.00-0.00 / kg	1kg	98% HPLC	100kg	Hangzhou ICH Biofarm Co., Ltd
	2019-07-06	9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate 206184-49-8	US $1.00 / KG	1G	98%	100KG	Career Henan Chemical Co

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
206184-49-8
US $0.00-0.00 / kg
98% HPLC
Hangzhou ICH Biofarm Co., Ltd

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
206184-49-8
US $1.00 / KG
98%
Career Henan Chemical Co

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Spectrum

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate(206184-49-8)¹HNMR

206184-49-8(9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate)Related Search:

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1of4

9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate Unii-99yxe507il Tenofovir Monohydrate Tenofovir (15 mg) Tenofovir (hydrate) [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid monohydrate PMPA Monohydrate (R)-(((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic acid hydrate (r)-[[2-(6-amino-9h-purin-9-yl)-1-methylethoxy]methyl]-phosphonic acid monohydrate (R)-9-(2-phosphonylmethoxy propyl)adenine(R-PMPA) [(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methylphosphonic acid R-PMPA of Tenofovir Tenofovir(H2O) Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1) 9-[(R)-2-(Phosphonomethoxy)propyl]adenine 1-hydrate Tenofovir (1643601) P-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid Hydrate Tenofovir hydrate (GS 1278) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid hydrate Tenofovir CRS 206184-49-8 C9H14N5O4PH2O C9H16N5O5P ALIMTA