caramiphen hydrogen edisilate
- CAS No.
- 125-86-0
- Chemical Name:
- caramiphen hydrogen edisilate
- Synonyms
- Ethanedisulfonate;BANIDACEBXZGNK-UHFFFAOYSA-N;Caramiphen ethanedisulfonate;caramiphen hydrogen edisilate;2-diethylaminoethyl 2-phenylcyclopentane-1-carboxylate;2-phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester;Bis[1-(carbo-β-diethylaminoethoxy)-1-phenylcyclopentane]ethanedisulfonate
- CBNumber:
- CB1877872
- Molecular Formula:
- 2C18H27NO2.C2H6O6S2
- Molecular Weight:
- 769.028
- MDL Number:
- MFCD00242609
- MOL File:
- 125-86-0.mol
| Melting point | 115-116° |
|---|---|
| FDA UNII | 09TQU5PG95 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
caramiphen hydrogen edisilate Chemical Properties,Uses,Production
Originator
Panparnit,Geigy,US,1949
Uses
Bis[1-(carbo-β-diethylaminoethoxy)-1-phenylcyclopentane]ethanedisulfonate is an anticholinergic and antiglutamatergic drug, which has also found use as an antidote against oragnophosphate poisoning.
Manufacturing Process
20.8 parts of 1-phenylcyclopentyl-1-carboxylic acid chloride, obtained from
the acid (cf. Am. Soc. 1934, 56, 715) by means of thionyl chloride, are
dissolved in 250 parts by volume of absolute ether, then, while stirring and
cooling with a mixture of common salt and ice a solution of 12 parts of
diethylaminoethanol in 50 parts by volume of absolute ether is allowed to
drop there into, the temperature being maintained below 0°C, whereupon
stirring is continued during 2 hours at room temperature. The whole is then
twice shaken out with water and once with diluted hydrochloric acid, the
combined aqueous solutions are made alkaline with a potassium carbonate
solution and shaken out with ether. The ethereal solution is washed with
water, dried over potassium carbonate and the solvent is distilled off. The base
boils at a pressure of 0.07 mm at 112°C to 115°C.
The base may then be converted to the hydrochloride or to the
ethanedisulfonic acid salt (edisylate).
Therapeutic Function
Antitussive
caramiphen hydrogen edisilate Preparation Products And Raw materials
caramiphen hydrogen edisilate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 029-81124267 15229202216 | 1073@dideu.com | China | 10011 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 58 |