ChemicalBook >> CAS DataBase List >>treosulfan
treosulfan
- CAS No.
- 299-75-2
- Chemical Name:
- treosulfan
- Synonyms
- CB-2562;Cb 40067;NSC 39069;Leo 40067;treosulfan;TREOSULPHAN;THREOSULFAN;Treosulfan D4;Dihydroxymyleran;Dihydroxybusulfan
- CBNumber:
- CB1926495
- Molecular Formula:
- C6H14O8S2
- Molecular Weight:
- 278.3
- MDL Number:
- MFCD02258964
- MOL File:
- 299-75-2.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| Melting point | 76-78 °C |
|---|---|
| Boiling point | 359.3°C (rough estimate) |
| Density | 1.305 (estimate) |
| refractive index | 1.5630 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 12.36±0.20(Predicted) |
| color | Off-White to Pale Beige |
| CAS DataBase Reference | 299-75-2 |
| NCI Dictionary of Cancer Terms | treosulfan |
| FDA UNII | CO61ER3EPI |
| IARC | 1 (Vol. 26, Sup 7, 100A) 2012 |
| NCI Drug Dictionary | treosulfan |
| ATC code | L01AB02 |
| Proposition 65 List | Treosulfan |
| EPA Substance Registry System | Treosulfan (299-75-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H340-H350-H361f |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| RIDADR | 2811 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LDLo intravenous in dog: 222mg/kg |
treosulfan price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1252 | Treosulfan ≥98% (HPLC) | 299-75-2 | 5mg | $70.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1252 | Treosulfan ≥98% (HPLC) | 299-75-2 | 25mg | $462 | 2024-03-01 | Buy |
| ChemScene | CS-3889 | Treosulfan ≥98.0% | 299-75-2 | 50mg | $550 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0024907 | TREOSULFAN 95.00% | 299-75-2 | 5MG | $660 | 2021-12-16 | Buy |
| ChemScene | CS-3889 | Treosulfan ≥98.0% | 299-75-2 | 5mg | $85 | 2021-12-16 | Buy |
treosulfan Chemical Properties,Uses,Production
Uses
Treosulfan is used as myeloablative agent in conditioning regimen prior to allogeneic hematopoietic stem cell transplantation (HSCT)??. It can also be an effective agent for conditioning children with inborn errors of immunity (IEI).
Definition
ChEBI: Treosulfan is a methanesulfonate ester.
General Description
Odorless white crystalline powder.
Air & Water Reactions
Water soluble. Slowly hydrolyzes: decomposes within 3 hours at pH 7.5 and 77°F. .
Fire Hazard
Flash point data for treosulfan are not available; however, treosulfan is probably combustible.
Clinical Use
Alkylating agent for ovarian cancer
Safety Profile
Confirmed carcinogen. Poison by intravenous route. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx.
Metabolism
Treosulfan is a prodrug of a bifunctional alkylating agent, converted in vivo to epoxide compounds. Approximately 30
% of the substance is excreted unchanged in the urine within 24 hours, nearly 90
% of which is within the first 6 hours after administration.
treosulfan Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 52)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1494 | 55 |
View Lastest Price from treosulfan manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-08 | Treosulfan
299-75-2
|
US $46.00-26.00 / kg | 1kg | 99.50% | 20tons | Wuhan Boyuan Import & Export Co., LTD | |
 |
2020-01-15 | treosulfan
299-75-2
|
US $1.00 / KG | 1KG | 98% | 1kg ,5kg, 50kg | Career Henan Chemical Co |
-
- Treosulfan
299-75-2
- US $46.00-26.00 / kg
- 99.50%
- Wuhan Boyuan Import & Export Co., LTD
-
- treosulfan
299-75-2
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
299-75-2(treosulfan)Related Search:
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THREOSULFAN
treosulfan
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Treosulfan (NSC-39069
Treosulfan D4
Treosulfan,inhibit,DNA Alkylator/Crosslinker,Inhibitor,NSC39069,NSC-39069
299-75-2
C6H14O6S
API