N-Boc-4-piperidinemethanol
- CAS No.
- 123855-51-6
- Chemical Name:
- N-Boc-4-piperidinemethanol
- Synonyms
- TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
- CBNumber:
- CB2100290
- Molecular Formula:
- C11H21NO3
- Molecular Weight:
- 215.29
- MDL Number:
- MFCD02094488
- MOL File:
- 123855-51-6.mol
- MSDS File:
- SDS
Melting point | 78-82 °C (lit.) |
---|---|
Boiling point | 308.0±15.0 °C(Predicted) |
Density | 1.059±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | soluble in Methanol |
form | Powder |
pka | 14.94±0.10(Predicted) |
color | White to brown |
InChI | InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3 |
InChIKey | CTEDVGRUGMPBHE-UHFFFAOYSA-N |
SMILES | N1(C(OC(C)(C)C)=O)CCC(CO)CC1 |
CAS DataBase Reference | 123855-51-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319 | |||||||||
Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 | |||||||||
Hazard Codes | Xi | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
N-Boc-4-piperidinemethanol price More Price(40)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 556017 | N-Boc-4-piperidinemethanol 97% | 123855-51-6 | 5g | $138 | 2023-06-20 | Buy |
TCI Chemical | B2364 | 1-(tert-Butoxycarbonyl)-4-piperidinemethanol >98.0%(GC) | 123855-51-6 | 1g | $17 | 2024-03-01 | Buy |
TCI Chemical | B2364 | 1-(tert-Butoxycarbonyl)-4-piperidinemethanol >98.0%(GC) | 123855-51-6 | 5g | $32 | 2024-03-01 | Buy |
Alfa Aesar | H26650 | 1-Boc-4-piperidinemethanol, 97% | 123855-51-6 | 5g | $95.65 | 2024-03-01 | Buy |
Alfa Aesar | H26650 | 1-Boc-4-piperidinemethanol, 97% | 123855-51-6 | 1g | $28 | 2021-12-16 | Buy |
N-Boc-4-piperidinemethanol Chemical Properties,Uses,Production
Chemical Properties
White to light brown solid
Uses
N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.
Application
N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.
General Description
N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.
N-Boc-4-piperidinemethanol Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Siyang Liaoning Biochemical Products Co. Ltd | +8615221114306 | 2594582574@qq.com | China | 574 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 | sales8@anhuiyiao.com | China | 253 | 58 |
Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 | alice@jndxj.com | China | 303 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 | 2691956269@qq.com | China | 349 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21700 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com | jocelynpan@zjarts.com | CHINA | 993 | 58 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
View Lastest Price from N-Boc-4-piperidinemethanol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-03-19 | N-BOC-4-piperidinemethanol
123855-51-6
|
US $0.00-0.00 / kg | 1kg | 99 | 50000KG/month | Shanghai Affida new material science and technology center | ||
2024-02-26 | N-Boc-4-piperidinemethanol
123855-51-6
|
US $0.00-0.00 / kg | 1kg | 98% | Tons | BTC Nantong Pharmaceuticals Technology Co.,Ltd | ||
2023-12-20 | N-Boc-4-piperidineMethanol
123855-51-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd |
- N-BOC-4-piperidinemethanol
123855-51-6
- US $0.00-0.00 / kg
- 99
- Shanghai Affida new material science and technology center
- N-Boc-4-piperidinemethanol
123855-51-6
- US $0.00-0.00 / kg
- 98%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
- N-Boc-4-piperidineMethanol
123855-51-6
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
123855-51-6(N-Boc-4-piperidinemethanol)Related Search:
1of4