ChemicalBook >> CAS DataBase List >>Polygalacic acid
Polygalacic acid
- CAS No.
- 22338-71-2
- Chemical Name:
- Polygalacic acid
- Synonyms
- Polygalacic;Polygalacicaci;Polygalacic acid;Virgaureagenin G;Polygalacic acid, >=98%;Virgaureagenin G，Polygalacic acid;(4R)-2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid;Polygalacic acid, 98%, from Polygala tenuifolia Willd.;(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid;Olean-12-en-28-oicacid, 2,3,16,23-tetrahydroxy-, (2β,3β,4,16)-
- CBNumber:
- CB21040708
- Molecular Formula:
- C30H48O6
- Molecular Weight:
- 504.7
- MDL Number:
- MFCD12911690
- MOL File:
- 22338-71-2.mol
Last updated:2023-06-08 09:03:02
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
Polygalacic acid price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 300805 | Polygalacic acid | 22338-71-2 | 20mg | $490 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0005843 | (2B,3B,4A,16A)-2,3,16,23-TETRAHYDROXYOLEAN-12-EN-28-OIC ACID 95.00% | 22338-71-2 | 5MG | $503.58 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 74064 | Polygalacicacid 98% | 22338-71-2 | 20mg | $533 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105678 | Polygalacic acid >98%,Standard References Grade | 22338-71-2 | 20mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594205 | Virgaureagenin G | 22338-71-2 | 5mg | $596.7 | 2021-12-16 | Buy |
Polygalacic acid Chemical Properties,Uses,Production
Uses
Polygalacic acid can be used to calm the nerves, eliminate phlegm, reduce swelling, etc. It is mostly used clinically to treat bronchitis, induce labor, and induce labor.
Biological Activity
Polygalacic acid is a triterpenoid tetrahydroxy acid isolated from Polygala paenea L.. It (0-100μM; 24h) can significantly reduce the mRNA expression of MMP-3, MMP-9, MMP-13 and COX-2, and the expression of these factors can be significantly increased by IL-1β in a dose-dependent manner .
in vitro
Polygalacic acid (0-100 μM; 24 hours) significantly decreases the mRNAexpressions of MMP-3, MMP-9, MMP-13, and COX-2, which are significantly increased by IL-1β, in a In a dose-dependent manner. Polygalacic acid (0-100 μM; 6 hours) decreases the expression of phosphor-p38, phosphor-Erk, and phosphor-Jnk induced by IL-1β, phosphor-p65 is not reduced by polygalacic acid.
RT-PCR
| Cell Line: | Chondrocyte cells |
| Concentration: | 50 μM; 100 μM |
| Incubation Time: | 24 hours |
| Result: | Suppressed IL-1β-induced COX-2, MMP3, MMP9, and MMP13 mRNA expression. |
Western Blot Analysis
| Cell Line: | Chondrocyte cells | Concentration: | 50 μM; 100 μM |
| Incubation Time : | 6 hours |
| Result: | Inhibited the IL-1β-induced activation of the MAPK pathway in chondrocytes. |
Polygalacic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 148)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from Polygalacic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Polygalacic acid
22338-71-2
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
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- Polygalacic acid
22338-71-2
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
22338-71-2(Polygalacic acid)Related Search:
Polygalacic acid
Polygalacic
(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid
Olean-12-en-28-oicacid, 2,3,16,23-tetrahydroxy-, (2β,3β,4,16)-
Virgaureagenin G
(4R)-2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid
Polygalacic acid or (2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid
Polygalacic acid
(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid
Polygalacic acid, >=98%
(4AR,5R,6aS,6bR,9R,10R,11S,12aR,12bR,14bR)-5,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12
Polygalacic acid, 98%, from Polygala tenuifolia Willd.
Polygalacicaci
Olean-12-en-28-oic acid, 2,3,16,23-tetrahydroxy-, (2β,3β,4α,16α)-
Virgaureagenin G，Polygalacic acid
22338-71-2
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract