INOS
- CAS No.
- Chemical Name:
- INOS
- Synonyms
- INOS;NOS2;NOS2A;NOS II;macNOS;NOS III;HEP-NOS;inducible;MACROPHAGE;EC 1.14.13.39
- CBNumber:
- CB2106409
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00803363
- MOL File:
- Mol file
| storage temp. | −70°C |
|---|---|
| form | buffered aqueous solution |
| NCI Dictionary of Cancer Terms | macrophage |
| FDA UNII | LLJ6UPO71A |
INOS price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N2783 | Nitric Oxide Synthase, Inducible from mouse recombinant, expressed in E. coli, buffered aqueous solution | 50units | $379 | 2024-03-01 | Buy | |
| Sigma-Aldrich | 482777 | Nitric Oxide Synthase, Inducible, Mouse, Recombinant, E. coli | 50U | $577 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1306705 | ANTI-NOS2A (CENTER) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 400μL | $461 | 2023-01-07 | Buy | |
| Sigma-Aldrich | SAB1305735 | ANTI-NOS2A(N-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 400μL | $461 | 2023-01-07 | Buy | |
| Cayman Chemical | 60864 | iNOS (mouse, recombinant) | 250U | $583 | 2024-03-01 | Buy |
INOS Chemical Properties,Uses,Production
Uses
Nitric Oxide Synthase, Inducible from mouse has been used in immunohistochemical studies. It is also used to evaluate the therapeutic efficacy of inducible nitric oxide synthase (NOS) on reperfusion-induced microcirculatory alterations and hemodynamic adverse effects in the microvasculature of skeletal muscle.
General Description
Inducible nitric oxide synthase (iNOS), also known as inflammatory nitric oxide synthase, is a calcium independent isoenzyme, involved in synthesis of nitric oxide (NO). It is a soluble enzyme encoded by the gene mapped to mouse chromosome 11. iNOS is active in dimeric form and its activity is induced by cytokines and various other stimuli. iNOS is expressed in various inflammatory conditions.
Biochem/physiol Actions
Tumor-derived inducible nitric oxide synthase (iNOS) plays a vital role in stimulating tumor growth and vessel maturation. Therefore, it is considered to be a potential therapeutic target for anti-vascular cancer therapies. Unchecked activity of iNOS leads to overproduction of nitric oxide (NO), which is toxic for living cells. iNOS activity can be controlled at both transcription and translational level by regulating protein stability, dimerization, phosphorylation, cofactor binding and availability of oxygen and L-arginine as substrates. iNOS plays a vital role in excisional wound repair and exhibits gene therapy strategy to advance wound healing process in iNOS-deficient conditions such as diabetes and steroid treatment.
INOS Preparation Products And Raw materials
Raw materials
Preparation Products
INOS Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| ChemeGen 中国 | 18818260767 | sales@chemegen.com | China | 6975 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| AntibodySystem | 027-65279366 18162686757 | biolab-reagents@atagenix.com | China | 9790 | 58 |