ChemicalBook >> CAS DataBase List >>Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide

Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide

CAS No.
2361742-30-3
Chemical Name:
Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide
Synonyms
VPC-70619;Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide
CBNumber:
CB210841086
Molecular Formula:
C16H8ClF3N4O
Molecular Weight:
364.71
MDL Number:
MOL File:
2361742-30-3.mol
Last updated:2023-05-21 10:59:17

Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide Properties

Boiling point 496.4±45.0 °C(Predicted)
Density 1.51±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 9.65±0.23(Predicted)

Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide Chemical Properties,Uses,Production

Biological Activity

VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration[1].

References

[1]. Ton AT, et al. Development of VPC-70619, a Small-Molecule N-Myc Inhibitor as a Potential Therapy for Neuroendocrine Prostate Cancer. Int J Mol Sci. 2022;23(5):2588. Published 2022 Feb 26.

Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5019 58
Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide VPC-70619 2361742-30-3