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CODEINONE

CAS No.
467-13-0
Chemical Name:
CODEINONE
Synonyms
C06171;CODEINONE;6-codeinone;6-Oxocodeine;OXYCODONE BASE;Oxycodone Related CoMpound C CII;Oxycodone USP Related Compound C;Codeine Monohydrate EP Impurity I;Codeinone (1.0mg/ml in Acetonitrile);Oxycodone Related Compound C CII (15 mg) (codeinone)
CBNumber:
CB2111371
Molecular Formula:
C18H19NO3
Molecular Weight:
297.35
MDL Number:
MFCD01714323
MOL File:
467-13-0.mol
Last updated:2023-06-08 09:03:01

CODEINONE Properties

Melting point 182-183°C
Boiling point 466.9±45.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Controlled Substance, -20°C Freezer
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 10 mg/ml
form A crystalline solid
pka 8.10±0.20(Predicted)
CAS DataBase Reference 467-13-0
FDA UNII 22B5AW0ANN

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Risk Statements  22
HS Code  2939190000
NFPA 704
0
4 0

CODEINONE Chemical Properties,Uses,Production

Chemical Properties

Brown Solid

Uses

A metabolite of Codeine (C634075). Controlled substance.

Uses

A metabolite of Codeine. Controlled substance

Definition

ChEBI: Codeinone is an isoquinoline alkaloid. It is functionally related to a morphine. It is a conjugate base of a codeinone(1+).

CODEINONE Preparation Products And Raw materials

Raw materials

Preparation Products

6-codeinone 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-on (5alpha)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-one (5a)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methyl-morphinan-6-one 6-Oxocodeine 7,8-Didehydro-4,5a-epoxy-3-methoxy-17-methyl-morphinan-6-one (5R)-3-Methoxy-7,8-didehydro-4,5-epoxy-17-methylmorphinan-6-one 3-Methoxy-17-methyl-4,5α-epoxy-7,8-didehydromorphinan-6-one 7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6-one 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one C06171 Oxycodone Related Compound C CII (15 mg) (codeinone) Oxycodone Related CoMpound C CII CODEINONE OXYCODONE BASE (4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one Codeinone (1.0mg/ml in Acetonitrile) Morphinan-6-one, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α)- Oxycodone Related Compound C CII (codeinone) (1485238) Codeine Monohydrate EP Impurity I Oxycodone USP Related Compound C 4,5α-epoxy-3-methoxy-17-methyl-7,8-didehydromorphinan-6-one(codeinone) Hydrocodone Hydrogen Tartrate 2.5-Hydrate Impurity E Hydrocodone Hydrogen Tartrate 2.5-Hydrate EP Impurity E 467-13-0 Pharmaceuticals Glucuronides Intermediates & Fine Chemicals Metabolites & Impurities