Asocainol
- CAS No.
- 77400-65-8
- Chemical Name:
- Asocainol
- Synonyms
- Go-4704;Goe-4704;Asocainol;6,7,8,9-Tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-5H-dibenz[d,f]azonin-1-ol;5H-Dibenz[d,f]azonin-1-ol, 6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-
- CBNumber:
- CB21117181
- Molecular Formula:
- C27H31NO3
- Molecular Weight:
- 417.54
- MDL Number:
- MFCD00864767
- MOL File:
- 77400-65-8.mol
FDA UNII | J40338OKKT |
---|
Asocainol price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A788500 | Asocainol | 77400-65-8 | 25mg | $1540 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007937 | ASOCAINOL 95.00% | 77400-65-8 | 25MG | $2194.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007937 | ASOCAINOL 95.00% | 77400-65-8 | 2.5MG | $742.5 | 2021-12-16 | Buy |
Asocainol Chemical Properties,Uses,Production
Originator
Asocainol,ZYF Pharm
Uses
Asocainol (ASOC) belongs to class I antiarrhythmic drugs, i.e., those that exert their action at the level of sodium channels of the myocardial cell membrane.
Uses
Labelled Asocainol
Manufacturing Process
A solution of a Grignard reagent is prepared from 5.5 g (0.23 mol) activated magnesium turnings and 41.5 g (0.24 mol) phenethyl bromide in 200 ml anhydrous diethyl ether. To this is added dropwise, at 35-40°C, a solution of 31.5 g (0.1 mol) thebaine in 0.4 liters dry benzene. After heating under reflux for 2 hours, the reaction mixture is decomposed with a solution of 48 g ammonium chloride in 200 ml water. The usual working up, after conversion of the base into the hydrochloride by means of hydrogen chloride in ethyl acetate, gives 7.3 g (21% of theory) (+/-)-2,12-dimethoxy-1-hydroxy-7- methyl-6-phenethyl-5,6,8,9-tetrahydro-7H-dibenz[d,f]azonine hydrochloride, melting point 227.6°C, after recrystallization from propan-2-ol.
Therapeutic Function
Antiarrhythmic
Asocainol Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56086 | 58 |
Hubei Nordina Biotechnology Co., Ltd. | 19371278702 | nuodinashengwu@163.com | China | 972 | 58 |