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6-BROMO-4-FLUORO INDOLE

6-BROMO-4-FLUORO INDOLE Structure
6-BROMO-4-FLUORO INDOLE structure
CAS No.
885520-59-2
Chemical Name:
6-BROMO-4-FLUORO INDOLE
Synonyms
6-BROMO-4-FLUORO INDOLE;4-Fluoro-6-bromo-indole;6-broMo-4-fluoro-1H-indole;1H-Indole, 6-broMo-4-fluoro-
CBNumber:
CB2111896
Molecular Formula:
C8H5BrFN
Molecular Weight:
214.03
MDL Number:
MFCD07781550
MOL File:
Mol file
MSDS File:
SDS
Last updated:2025-07-24 18:13:52
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6-BROMO-4-FLUORO INDOLE Properties

Boiling point 315.1±22.0 °C(Predicted)
Density 1.750±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 15.47±0.30(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933998090

6-BROMO-4-FLUORO INDOLE price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B804275 6-Bromo-4-fluoro-1H-indole 885520-59-2 1mg $45 2021-12-16 Buy
TRC B804275 6-Bromo-4-fluoro-1H-indole 885520-59-2 2mg $60 2021-12-16 Buy
Biosynth Carbosynth FB105513 6-Bromo-4-fluoro-1H-indole 885520-59-2 100mg $150 2021-12-16 Buy
Biosynth Carbosynth FB105513 6-Bromo-4-fluoro-1H-indole 885520-59-2 250mg $250 2021-12-16 Buy
Apolloscientific PC53423 6-Bromo-4-fluoro-1H-indole 885520-59-2 250mg $350 2021-12-16 Buy
Product number Packaging Price Buy
B804275 1mg $45 Buy
B804275 2mg $60 Buy
FB105513 100mg $150 Buy
FB105513 250mg $250 Buy
PC53423 250mg $350 Buy

6-BROMO-4-FLUORO INDOLE Chemical Properties,Uses,Production

Synthesis

N,N-Dimethylformamide diisopropyl acetal

18503-89-4

4-BROMO-2-FLUORO-6-NITROTOLUENE

502496-34-6

6-BROMO-4-FLUORO INDOLE

885520-59-2

To a dry 100 mL round bottom flask was added 4-bromo-2-fluoro-6-nitrotoluene (1.3 g, 5.56 mmol, 1 eq.), N,N-dimethylformamide diisopropyl acetal (2.6 mL, 12.22 mmol, 2.2 eq.), triethylamine (0.85 mL, 6.11 mmol, 1.1 eq.) and anhydrous DMF (5 mL). The mixture was stirred at 130 °C for 2 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and the residue was dissolved in a solvent mixture of toluene (30 mL) and acetic acid (40 mL). Iron powder (6.2 g, 11.10 mmol, 20 eq.) and silica (6 g) were then added. The dark red mixture was heated to 100 °C under vigorous stirring and maintained for 30 min. After the reaction mixture was cooled to room temperature, it was diluted with EtOAc, filtered and the solid was washed thoroughly with EtOAc. The combined filtrates were washed sequentially with saturated aqueous NaHCO3, aqueous Na2S2O3, saturated aqueous NaHCO3 and brine, dried over Na2SO4 and concentrated under reduced pressure. Purification of the residue by fast column chromatography (20% DCM in hexane solution) afforded 6-bromo-4-fluoro-1H-indole (814 mg, 3.75 mmol, 68% yield; UPLC purity: 99%).

References

[1] Patent: WO2016/180537, 2016, A1. Location in patent: Page/Page column 181; 182

6-BROMO-4-FLUORO INDOLE Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide diisopropyl acetal 4-BROMO-2-FLUORO-6-NITROTOLUENE Acetic acid N,N-Dimethylformamide Triethylamine
Toluene Iron

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Preparation Products

6-BROMO-4-FLUORO INDOLE Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
SHANGHAI FLUORORING PHARMACEUTICAL CO LTD 		17501600223 sales@fluororing.com China 75 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		+8618795957998 karmelhk@126.com CHINA 2886 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8647 58
Nanjing Yushan Wanfang Biotechnology Co., Ltd. 		+86-025-84918180 +86-18014482516 3552541679@qq.com China 997 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
Supplier Advantage
SHANGHAI FLUORORING PHARMACEUTICAL CO LTD 		58
ATK CHEMICAL COMPANY LIMITED 		60
Accela ChemBio Inc. 		58
career henan chemical co 		58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
CR Corporation Limited 		58
Nanjing Yushan Wanfang Biotechnology Co., Ltd. 		58
Coresyn Pharmatech Co., Ltd. 		58
PT CHEM GROUP LIMITED 		58

View Lastest Price from 6-BROMO-4-FLUORO INDOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Fluoro-6-bromo-indole pictures 2025-07-02 4-Fluoro-6-bromo-indole
885520-59-2
 US $0.00-0.00 / kg 1kg 99 100 SHANGHAI FLUORORING PHARMACEUTICAL CO LTD
6-BROMO-4-FLUORO INDOLE pictures 2020-01-01 6-BROMO-4-FLUORO INDOLE
885520-59-2
 US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

6-BROMO-4-FLUORO INDOLE Spectrum

6-BROMO-4-FLUORO INDOLE(885520-59-2)1HNMR

885520-59-2(6-BROMO-4-FLUORO INDOLE)Related Search:

1H-Indole, 4-broMo-6-(trifluoroMethyl)- 1H-Indole, 6-broMo-4-(phenylMethoxy)- 4-BROMO-6-AMINOINDOLE 1H-Indole, 6-broMo-4-nitro- 6-Chloro-4-methoxyindole
1H-Indol-4-amine,6-iodo-(9CI) 6-Bromo-1H-indol-4-amine

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6-BROMO-4-FLUORO INDOLE 1H-Indole, 6-broMo-4-fluoro- 6-broMo-4-fluoro-1H-indole 4-Fluoro-6-bromo-indole 885520-59-2