FACTOR XA
- CAS No.
- 9002-05-5
- Chemical Name:
- FACTOR XA
- Synonyms
- FACTOR XA;EC 3.4.21.6;HUMAN FACTOR XA;FACTOR XA, HUMAN;BOVINE FACTOR XA;FACTOR XA (BOVINE);COAGULATION FACTOR XA;FACTOR XA, BOVINE PLASMA;FACTOR XA, BOVINE, 50 UG;FACTOR XA, BOVINE, 250 UG
- CBNumber:
- CB2112747
- Molecular Formula:
- C217H342N68O60S3
- Molecular Weight:
- 4959.65198
- MDL Number:
- MFCD00166312
- MOL File:
- 9002-05-5.mol
| storage temp. | -20°C |
|---|---|
| form | aqueous glycerol solution |
| FDA UNII | HYF6HN9XGQ |
FACTOR XA price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F9302 | Factor X Activated (Xa) from bovine plasma aqueous glycerol solution | 9002-05-5 | 50μg | $180 | 2024-03-01 | Buy |
| Sigma-Aldrich | 233526 | Coagulation Factor Xa, Human Plasma, CAS 9002-05-5, is a native coagulation factor Xa prepared from Factor X by activation with Russel's viper venom. The venom is removed after activation. | 9002-05-5 | 10u | $315 | 2024-03-01 | Buy |
| Usbiological | F0018-16 | Factor Xa, Bovine | 9002-05-5 | 100ug | $283 | 2021-12-16 | Buy |
| Usbiological | F0018-15 | Factor Xa, Human | 9002-05-5 | 100ug | $312 | 2021-12-16 | Buy |
| Usbiological | 301203 | Factor Xa, Human | 9002-05-5 | 400ug | $563 | 2021-12-16 | Buy |
FACTOR XA Chemical Properties,Uses,Production
Uses
Fusion proteins are commonly expressed with a factor Xa cleavable Ile-Glu (or Asp)-Gly-Arg-↓-X sequence. Typically 1 mg of fusion protein can be incubated with 10 μg of factor Xa for 2.5 hours at 37 °C.
General Description
Native coagulation factor Xa from human plasma prepared from homogeneous Factor X by activation with Russel’s viper venom. Hydrolyzes peptide and ester bonds at the carboxyl group of arginine. Specifically catalyzes the activation of prothrombin to thrombin. Prothrombin activation is accelerated by Factor Va, phospholipids, and Ca2+. Factor Xa was prepared from homogeneous Factor X, using Russels′ viper venom (RVV), which was removed after activation. Inhibited by AEBSF (Cat. No. 101500), DFP (Cat. No. 30967), PMSF (Cat. No. 52332), and soybean trypsin inhibitor (Cat. No. 650357). Sold on the basis of plasma equivalent units of Factor X. 100 plasma equivalent units are equal to 800 μg of Factor X.
Biochem/physiol Actions
Factor Xa catalyzes the hydrolysis of the Arg-Thr and then Arg-Ile bonds in prothrombin to yield active thrombin.The fairly strict recognition sequence is Ile-Glu (or Asp)-Gly-Arg-↓-X.It may sometimes cleave at other basic residues, depending on the conformation of the target protein. Factor Xa will not cleave if a proline residue follows the arginine of the recognition sequence.pH Optimum: 7.6-8.0Temperature Optimum: 37 °C
FACTOR XA Preparation Products And Raw materials
Raw materials
Preparation Products
FACTOR XA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Sigma-Aldrich | 80 |
| Guangzhou Tomums Life Science Co., Ltd. | 58 |
| United States Biological | 58 |
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