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ChemicalBook >> CAS DataBase List >>(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Structure
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide structure
CAS No.
135729-78-1
Chemical Name:
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Synonyms
Palonosetron Impurity 3;Palonosetron Impurity 25;Palonosetron Impurity 27;Palonosetron Impurity 20;Palonosetron Impurity 1;Palonosetron Intermediate;(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra;(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide;N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide;(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
CBNumber:
CB21135547
Molecular Formula:
C18H24N2O
Molecular Weight:
284.4
MDL Number:
MFCD27923863
MOL File:
135729-78-1.mol
Last updated:2023-04-23 13:52:06
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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Properties

Melting point 157-159oC
Boiling point 439.2±45.0 °C(Predicted)
Density 1.17
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 14.75±0.20(Predicted)
color White

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A795320 (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1 1g $910 2021-12-16 Buy
Medical Isotopes, Inc. 63045 N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1 250mg $1250 2021-12-16 Buy
American Custom Chemicals Corporation CHM0372970 5,6,7,8-TETRAHYDRO-NAPHTHALENE-1-CARBOXYLIC ACID (1-AZA-BICYCLO[2.2.2]OCT-3-YL)-AMIDE 95.00% 135729-78-1 5MG $504.97 2021-12-16 Buy
Medical Isotopes, Inc. 63045 N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1 25mg $650 2021-12-16 Buy
Crysdot CD11279770 (S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide 95+% 135729-78-1 1g $683 2021-12-16 Buy
Product number Packaging Price Buy
A795320 1g $910 Buy
63045 250mg $1250 Buy
CHM0372970 5MG $504.97 Buy
63045 25mg $650 Buy
CD11279770 1g $683 Buy

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Chemical Properties,Uses,Production

Uses

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide synthesis

110808-69-0
120570-05-0
135729-78-1
Synthesis of (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide from 5,6,7,8-TETRAHYDRO-NAPHTHALENE-1-CARBONYL CHLORIDE and (S)-quinuclidin-3-aMine

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

5,6,7,8-TETRAHYDRO-NAPHTHALENE-1-CARBONYL CHLORIDE 5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid (S)-quinuclidin-3-aMine Oxalyl chloride

Preparation Products

Palonosetron

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Suppliers

Global( 79)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418684 +8618949823763 sales@tnjchem.com China 25363 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 50000 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Supplier Advantage
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
sgtlifesciences pvt ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
GIHI CHEMICALS CO.,LIMITED 		58
China National Standard Pharmaceutical Corporation Limited 		58
Amadis Chemical Company Limited 		58

View Lastest Price from (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide pictures 2020-02-21 (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
135729-78-1
 US $3.00 / KG 1KG 98% 200KG Career Henan Chemical Co
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide pictures 2020-02-01 (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
135729-78-1
 US $1.00 / KG 1KG 98% 200kgs Career Henan Chemical Co

135729-78-1((S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide)Related Search:

Formamide,Deionized N,N-Dimethylformamide Formamide Benzamide Chlorantraniliprole
5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid PLSQ-001 TM4-QJ Palonosetron Impurity 6 HCl Palonosetron Impurity 8 Palonosetron impurity
Palonosetron Impurity 7 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- N,N-Diethyl-5,6,7,8-tetrahydronaphthalene-1-carboxamide (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxaMide-d1 (3S)-AMinoquinuclidine-D1 Dihydrochloride
2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline (R,S)-Palonosetron Hydrochloride (6R)-Hydroxy (R,S)-Palonosetron

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(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide (S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxaMide N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 5,6,7,8-tetrahydronaphthalene-1-carboxamide Palonosetron Impurity 3 Palonosetron Intermediate Palonosetron Impurity 20 Palonosetron Impurity 27 N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide Palonosetron Impurity 25 Palonosetron Impurity 1 1-Naphthalenecarboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro- (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra 135729-78-1 Intermediate of palonosetron hcl