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ACIFRAN

CAS No.
72420-38-3
Chemical Name:
ACIFRAN
Synonyms
ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
CBNumber:
CB2121167
Molecular Formula:
C12H10O4
Molecular Weight:
218.21
MDL Number:
MFCD00865746
MOL File:
72420-38-3.mol
Last updated:2023-09-04 15:51:00

ACIFRAN Properties

Melting point 176°
Boiling point 378.4±42.0 °C(Predicted)
Density 1.343±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility Soluble in DMSO > 10 mM
form Powder
pka 2.25±0.40(Predicted)
FDA UNII B1X701S0MV

SAFETY

Risk and Safety Statements

Toxicity LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)

ACIFRAN price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1762 Acifran ≥99%(HPLC) 72420-38-3 10 $152 2021-12-16 Buy
Tocris 1762 Acifran ≥99%(HPLC) 72420-38-3 50 $622 2021-12-16 Buy
TRC A795258 Acifran 72420-38-3 5mg $360 2021-12-16 Buy
Usbiological 254534 Acifran 72420-38-3 10mg $409 2021-12-16 Buy
ApexBio Technology B6848 Acifran 72420-38-3 10mg $234 2021-12-16 Buy
Product number Packaging Price Buy
1762 10 $152 Buy
1762 50 $622 Buy
A795258 5mg $360 Buy
254534 10mg $409 Buy
B6848 10mg $234 Buy

ACIFRAN Chemical Properties,Uses,Production

Uses

Antihyperlipopro-teinemic.

Uses

Acifran is a nicotinic acid receptor agonist.

brand name

Reductol (Wyeth-Ayerst).

Biological Activity

Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.

storage

Store at +4°C

ACIFRAN Preparation Products And Raw materials

Raw materials

Preparation Products

ACIFRAN Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2983 58
BOC Sciences -- info@bocsci.com USA 0 65
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613 sales@chemrenpharm.com China 3538 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58

ACIFRAN Spectrum

ay25712 ACIFRAN 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid 4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid Acifranum 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl- 72420-38-3 Miscellaneous Compounds