ChemicalBook >> CAS DataBase List >>2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide

CAS No.
100130-32-3
Chemical Name:
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide
Synonyms
VUF8430 hydrobromide;VUF 8430 dihydrobromide >=97% (NMR);2-guanidinoethyl carbamimidothioate dihydrobromide;2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester;2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide;Carbamimidothioic acid, 2-[(aminoiminomethyl)amino]ethyl ester, dihydrobromide (9CI)
CBNumber:
CB21256039
Molecular Formula:
C4H13Br2N5S
Molecular Weight:
0
MDL Number:
MFCD01694605
MOL File:
100130-32-3.mol
Last updated:2023-06-30 15:45:59

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Properties

storage temp. room temp
solubility deionized water: soluble24mg/mL
form solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
RTECS  UM6960000
NFPA 704
0
2 0

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V4390 VUF 8430 dihydrobromide ≥97% (NMR) 100130-32-3 5mg $97.2 2024-03-01 Buy
Sigma-Aldrich V4390 VUF 8430 dihydrobromide ≥97% (NMR) 100130-32-3 25mg $382 2023-01-07 Buy
Cayman Chemical 27682 VUF8430 (hydrobromide) 100130-32-3 1mg $37 2024-03-01 Buy
Cayman Chemical 27682 VUF8430 (hydrobromide) 100130-32-3 5mg $81 2024-03-01 Buy
Cayman Chemical 27682 VUF8430 (hydrobromide) 100130-32-3 10mg $142 2024-03-01 Buy
Product number Packaging Price Buy
V4390 5mg $97.2 Buy
V4390 25mg $382 Buy
27682 1mg $37 Buy
27682 5mg $81 Buy
27682 10mg $142 Buy

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Chemical Properties,Uses,Production

Description

VUF8430 is a histamine H4 receptor agonist (Ki = 31.6 nM). It is selective for histamine H4 over H1 and H3 receptors in radioligand binding assays (Kis = >1 and 1 μM, respectively) and is less active in isolated guinea pig atria, which endogenously expresses high levels of H2 receptors (pD2 = 3.8). VUF8430 inhibits forskolin-induced, cAMP-mediated increases in β-galactosidase activity (EC50 = 50.1 nM). In vivo, VUF8430 (30 mg/kg) enhances HCl-induced formation of gastric lesions in rats. It also reduces mechanical and thermal allodynia in a mouse model of peripheral neuropathy induced by spared nerve injury (SNI).

Uses

VUF 8430 Dihydrobromide is an H4 receptor agonist.

storage

Desiccate at RT

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6037 18920794737 sales@heowns.com China 20506 60
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide 2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester 2-guanidinoethyl carbamimidothioate dihydrobromide VUF 8430 dihydrobromide >=97% (NMR) VUF8430 hydrobromide Carbamimidothioic acid, 2-[(aminoiminomethyl)amino]ethyl ester, dihydrobromide (9CI) 100130-32-3 C4H13Br2N5S