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Azlocillin sodium

Azlocillin sodium structure

CAS No.: 37091-65-9

Chemical Name:: Azlocillin sodium

Synonyms: AZLOCILLIN SODIUM SALT;securopen;Prestwick_48;sodium azlocillin;AZLOCILLIN SODIUM;AZLOCILLINE SODIUM;Aloxicillin sodium;monosodiumazlocillin;D-alpha-([Imidazolidin;Azlocillin sodium, >=95%

CBNumber:: CB2128131

Molecular Formula:: C20H22N5NaO6S

Molecular Weight:: 483.47

MDL Number:: MFCD07793330

MOL File:: 37091-65-9.mol

Last updated:2023-07-13 12:29:27

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Azlocillin sodium Properties

Melting point	>199oC (dec.)
Flash point	>110°(230°F)
storage temp.	Inert atmosphere,2-8°C
solubility	H2O: soluble50mg/mL
form	powder
color	White to Off-White
Water Solubility	Freely soluble in water
Stability	Hygroscopic
CAS DataBase Reference	37091-65-9(CAS DataBase Reference)
FDA UNII	DWV1EFW947

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H317-H334
Precautionary statements	P280-P302+P352
Hazard Codes	Xn
Risk Statements	42/43
Safety Statements	36
WGK Germany	3
RTECS	XH9250000
Toxicity	mouse,LD50,intramuscular,15420mg/kg (15420mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: TREMORBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX),Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. Vol. 32, Pg. 453, 1987.

Azlocillin sodium price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A7926	Azlocillin sodium salt	37091-65-9	1g	$149	2024-03-01	Buy
Sigma-Aldrich	A7926	Azlocillin sodium salt	37091-65-9	5g	$521	2023-06-20	Buy
Alfa Aesar	J66895	Azlocillin sodium, 90%	37091-65-9	10g	$343	2021-12-16	Buy
Alfa Aesar	J66895	Azlocillin sodium, 90%	37091-65-9	1g	$37.1	2021-12-16	Buy
Cayman Chemical	18424	Azlocillin (sodium salt) ≥95%	37091-65-9	250mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
A7926	1g	$149	Buy
A7926	5g	$521	Buy
J66895	10g	$343	Buy
J66895	1g	$37.1	Buy
18424	250mg	$32	Buy

Azlocillin sodium Chemical Properties,Uses,Production

Originator

Securopen,Bayer,W. Germany,1977

Uses

Antibacterial;Bacterial transpeptidase inhibitor

Uses

Azlocillin sodium is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques.

Definition

ChEBI: Azlocillin sodium is an organic sodium salt. It contains an azlocillin(1-).

Manufacturing Process

3.8 parts by weight of D-(-)-α-[(imidazolidin-2-on-1-yl)carbonylamino]phenylacetic acid were dissolved in 65 parts by volume of dichloromethane. 2.7 parts by weight of 1-methyl-2-chloro-δ1-pyrrolinium chloride were added, and after cooling to -10°C 2.0 parts by volume of triethylamine were added gradually. This reaction mixture was then stirred for one hour at -5°C (mixture A). 4.0 parts by weight of 6-aminopenicillanic acid in 80 parts by volume of dichloromethane were treated with 4.4 parts by volume of triethylamine and 4.0 parts by weight of anhydrous sodium sulfate and then stirred for two hours at room temperature. After filtration, the solution was cooled to -20°C and combined with the mixture A. The reaction mixture was left to reach 0°C of its own accord, and was then stirred for a further hour at 0°C. The solvent was removed in a rotary evaporator, the residue was dissolved in water, and the solution was covered with a layer of ethyl acetate and acidified with dilute hydrochloric acid at 0° to 5°C, while stirring, until pH 1.5 was reached. The organic phase was then separated off, washed with water, dried over magnesium sulfate while cooling, and filtered, and after dilution with an equal amount of ether the sodium salt of the penicillin was precipitated from the filtrate by adding a solution of sodium 2-ethylcaproate dissolved in ether containing methanol. Yield: 1.3 parts by weight.

brand name

Azlin (Bayer).

Therapeutic Function

Antibacterial

Azlocillin sodium synthesis

Synthesis of Azlocillin sodium from Azlocillin

Azlocillin sodium Preparation Products And Raw materials

Raw materials

6-Aminopenicillanic acid Azlocillin

Preparation Products

Azlocillin sodium Suppliers

Global( 269)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Hangzhou ICH Biofarm Co., Ltd	+undefined8613073685410	sales@ichemie.com	China	985	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3834	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Xiamen AmoyChem Co., Ltd	58
HubeiwidelychemicaltechnologyCo.,Ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58

View Lastest Price from Azlocillin sodium manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-11-01	Azlocillin sodium 37091-65-9	US $0.00-0.00 / kg	1kg	99.0%	20 tons	Hangzhou ICH Biofarm Co., Ltd
2023-07-01	Azlocillin sodium 37091-65-9	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-03-17	Azlocillin Sodium 37091-65-9	US $10.00 / KG	1KG	99%	10 mt	Hebei Guanlang Biotechnology Co., Ltd.

Azlocillin sodium
37091-65-9
US $0.00-0.00 / kg
99.0%
Hangzhou ICH Biofarm Co., Ltd

Azlocillin sodium
37091-65-9
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Azlocillin Sodium
37091-65-9
US $10.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

Azlocillin sodium Spectrum

Azlocillin sodium(37091-65-9)¹HNMR

37091-65-9(Azlocillin sodium)Related Search:

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Dimethyl sulfide Dimethyl fumarate Azlocillin N-ACETYL-L-TYROSINE ETHYL ESTER Sodium formate

Sodium bicarbonate N,N-Dimethylformamide Acetylferrocene Sodium carbonate Ampicillin sodium

Ampicillin Dimethyl phthalate Penicillin G

1of4

sodium [2S-[2alpha,5alpha,6beta(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sterile Azlocillin sodium AZLOCILLINE SODIUM d-α-([imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin sodium azlocillin sodium [2s-[2a,5a,6b(s*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-,monosodiumsalt,( 5-alpha,6-beta(s*)))-2s-(2-alph monosodiumazlocillin securopen (2S,5β)-3,3-Dimethyl-7-oxo-6α-[[(R)-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid sodium salt D-alpha-([Imidazolidin Prestwick_48 Azlocillin sodium salt,D-α-([Imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin Azlocillin Sodium (200 mg) 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, sodium salt (1:1), (2S,5R,6R)- Azlocillin sodium, >=95% Sodium [2S-[2a,5a,6b(S*)]]-3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxy D-ALPHA-[(IMIDAZOLIDIN-2-ON-1-YL)-CARBONYLAMINO]BENZYLPENICILLIN D-A-([IMIDAZOLIDIN-2-ON-1-YL]CARBONYLAMINO)BENZYLPENICILLIN AZLOCILLIN SODIUM 3,3-dimethyl-7-oxo-6-[[[[(2-oxoimidazolidin-1-yl)carbonyl]amino]phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2S)-1-oxo-2-[[oxo-(2-oxo-1-imidazolidinyl)methyl]amino]-2-phenylethyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-((R)-2-(2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Azlocillin sodium USP/EP/BP Azlocillin Sodium Salt (1.0mg/ml in DMSO) AzlocillinSodiumQ: What is AzlocillinSodium Q: What is the CAS Number of AzlocillinSodium Q: What is the storage condition of AzlocillinSodium Q: What are the applications of AzlocillinSodium AZLOCILLIN SODIUM SALT Phenylephrine Impurity 105-d3 Aloxicillin sodium 37091-65-9 C20H22N5NaO6S C20H23N5O6SNa C20H22N5O6SNa Antibiotics A-F Antibiotics A to Z Antibiotics BioChemical Active Pharmaceutical Ingredients Miscellaneous 37091-65-9