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2-amino-4-phosphonobutyric acid

CAS No.
6323-99-5
Chemical Name:
2-amino-4-phosphonobutyric acid
Synonyms
2-Amino-4-phosphonobutanoic acid;Butanoic acid, 2-amino-4-phosphono-;DL-2-Amino-4-phosphonobutyric Acid, 98.0+ % (HPLC)
CBNumber:
CB21333718
Molecular Formula:
C4H10NO5P
Molecular Weight:
183.1
MDL Number:
MFCD00013999
MOL File:
6323-99-5.mol
Last updated:2023-06-30 15:45:59

2-amino-4-phosphonobutyric acid Properties

Melting point 229-231 °C(Solv: ethanol (64-17-5); water (7732-18-5))
Boiling point 491.7±55.0 °C(Predicted)
Density 1.628±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility Water:9.15(Max Conc. mg/mL);50.0(Max Conc. mM)
form White solid.
pka 2.19±0.10(Predicted)
Water Solubility Soluble to 50 mM in water
FDA UNII H8B59H10OK

2-amino-4-phosphonobutyric acid price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29011 DL-AP4 6323-99-5 50mg $39 2024-03-01 Buy
Cayman Chemical 29011 DL-AP4 6323-99-5 100mg $73 2024-03-01 Buy
Cayman Chemical 29011 DL-AP4 6323-99-5 250mg $172 2024-03-01 Buy
Cayman Chemical 29011 DL-AP4 6323-99-5 500mg $322 2024-03-01 Buy
TRC A627558 DL-2-Amino-4-phosphonobutanoicacid(AP4) 6323-99-5 10mg $420 2021-12-16 Buy
Product number Packaging Price Buy
29011 50mg $39 Buy
29011 100mg $73 Buy
29011 250mg $172 Buy
29011 500mg $322 Buy
A627558 10mg $420 Buy

2-amino-4-phosphonobutyric acid Chemical Properties,Uses,Production

Description

DL-AP4 is a broad-spectrum glutamatergic antagonist. DL-AP4 (2.5 mM) inhibits electrically stimulated synaptic transmission in rabbit hippocampal slices. It also depresses depolarizations induced by NMDA , L-homocysteate, or kainate in isolated frog spinal cord when used at a concentration of 1 mM. DL-AP4 (0.2 mM) inhibits the accumulation of inositol induced by ibotenate , quisqualate, L-glutamate, and L-aspartate in rat hippocampal slices.

Uses

DL-2-Amino-4-phosphonobutanoic acid (AP4) is an amino-acid derivative reported to block cone signals in the rat retina. Improves learning and memory processes in passive and active avoidance situations in rats.

storage

Store at RT

107257-47-6
6323-99-5
Synthesis of 2-amino-4-phosphonobutyric acid from Propanedioic acid, 2-(acetylamino)-2-[2-(diethoxyphosphinyl)ethyl]-, 1,3-diethyl ester

2-amino-4-phosphonobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-4-phosphonobutyric acid Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
Nextpeptide Inc
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Shanxi Tihondan Pharmaceutical Technology Co., Ltd
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Aladdin Scientific
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Aikon International Limited 025-66113011 18112977050 cb6@aikonchem.com China 15495 58
SuZhou Medinoah Co.,LTD. 0512-0512-69561983 13914027025 he_qf@medinoah.com China 3380 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 2996 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2488 58
2-Amino-4-phosphonobutanoic acid DL-2-Amino-4-phosphonobutyric Acid, 98.0+ % (HPLC) Butanoic acid, 2-amino-4-phosphono- 6323-99-5