Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>LY 223982

LY 223982

LY 223982 Structure
LY 223982 structure
CAS No.
117423-74-2
Chemical Name:
LY 223982
Synonyms
CGS23131;LY 223982;SKF107324);LY223982,LY-223982;LY223982 Exclusive;SYZSSLLFRVDRHL-QPJJXVBHSA-N;LY223982 (Synonyms: CGS23131;5-(3-Carboxybenzoyl)-2-[(E)-6-(4-methoxyphenyl)-5-hexenyloxy]benzenepropanoic acid;Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]-
CBNumber:
CB21341434
Molecular Formula:
C30H30O7
Molecular Weight:
502.55
MDL Number:
MFCD00876442
MOL File:
117423-74-2.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19
Request For Quotation

LY 223982 Properties

Melting point 151-152 °C
Boiling point 753.8±60.0 °C(Predicted)
Density 1.235±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly, Heated, Sonicated), DMSO (Very Slightly)
form A crystalline solid
pka 3.81±0.10(Predicted)
FDA UNII XG52JC545T

LY 223982 price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010024 LY223982 ≥98% 117423-74-2 1mg $28 2024-03-01 Buy
Cayman Chemical 10010024 LY223982 ≥98% 117423-74-2 5mg $117 2024-03-01 Buy
Cayman Chemical 10010024 LY223982 ≥98% 117423-74-2 10mg $207 2024-03-01 Buy
Cayman Chemical 10010024 LY223982 ≥98% 117423-74-2 25mg $448 2024-03-01 Buy
TRC L503108 LY223982 117423-74-2 1mg $40 2021-12-16 Buy
Product number Packaging Price Buy
10010024 1mg $28 Buy
10010024 5mg $117 Buy
10010024 10mg $207 Buy
10010024 25mg $448 Buy
L503108 1mg $40 Buy

LY 223982 Chemical Properties,Uses,Production

Description

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from the 5-lipoxygenase pathway of arachidonic acid metabolism and is an important mediator of the inflammatory process. The benzophenone dicarboxylic acid derivative LY223982 is a potent BLT1 receptor antagonist. It inhibits the specific binding of radiolabeled-LTB4 to isolated human neutrophils with an IC50 value of 13.2 nM. LY223982 inhibits the leukotriene B4 (LTB4)-induced aggregation of guinea pig and human neutrophils with IC50 values of 74 and 100 nM, respectively. However, concentrations of LY223982 up to 10 μM do not inhibit binding of LTB4 to human BLT1 or BLT2 expressed in CHO cells.

Uses

LY223982 is a potent P2Y7 (BLT1) receptor antagonist.

LY 223982 Preparation Products And Raw materials

Raw materials

Preparation Products

LY 223982 Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3421 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Angel Pharmatech, Ltd. 17317130613 3358272972@qq.com China 3238 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18488 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Angel Pharmatech, Ltd. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
DC Chemicals 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Changzhou Bojia Biomedical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58

117423-74-2(LY 223982)Related Search:

LY 223982 3-(3-FORMYLPHENYL)PROPANOIC ACID METHOXYPHENONE 4-METHOXY-3'-METHYLBENZOPHENONE 3-(2-METHOXYPHENYL)PROPIONIC ACID
LY 223982 5-(3-Carboxybenzoyl)-2-[(E)-6-(4-methoxyphenyl)-5-hexenyloxy]benzenepropanoic acid SYZSSLLFRVDRHL-QPJJXVBHSA-N LY223982 Exclusive LY223982 (Synonyms: CGS23131 SKF107324) CGS23131 Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]- LY223982,LY-223982 117423-74-2