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tyvelose

CAS No.
5658-12-8
Chemical Name:
tyvelose
Synonyms
tyvelose;D-Tyvelose;3,6-Dideoxy-;3,6-Dideoxy-D-mannose;D-arabino-Hexose, 3,6-dideoxy-
CBNumber:
CB21346297
Molecular Formula:
C6H12O4
Molecular Weight:
148.16
MDL Number:
MFCD09750748
MOL File:
5658-12-8.mol
Last updated:2023-05-18 11:31:05

tyvelose Properties

Melting point NA
Boiling point 125-150 °C(Press: 0.05 Torr)
Density 1.249±0.06 g/cm3(Predicted)
storage temp. Refrigerator, Under Inert Atmosphere
solubility Methanol (Slightly), Water (Slightly)
form Solid
pka 13.08±0.20(Predicted)
color Off-White to Pale Beige
Stability Hygroscopic

tyvelose price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20910 Tyvelose ≥95% 5658-12-8 1mg $81 2024-03-01 Buy
Cayman Chemical 20910 Tyvelose ≥95% 5658-12-8 5mg $143 2024-03-01 Buy
Cayman Chemical 20910 Tyvelose ≥95% 5658-12-8 10mg $257 2024-03-01 Buy
TRC T948000 Tyvelose 5658-12-8 25mg $325 2021-12-16 Buy
Usbiological 022632 Tyvelose 5658-12-8 10mg $446 2021-12-16 Buy
Product number Packaging Price Buy
20910 1mg $81 Buy
20910 5mg $143 Buy
20910 10mg $257 Buy
T948000 25mg $325 Buy
022632 10mg $446 Buy

tyvelose Chemical Properties,Uses,Production

Description

Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans. It is produced in high amounts by the infective larva and is immunodominant during the muscle stage of infection. Mice immunized with tyvelose-BSA produce IgG1 antibodies to tyvelose but are not resistant to infection by T. spiralis. Tyvelose-specific antibodies (2.5 mg/20 g) administered to rat pups leads to expulsion of first stage larvae from the intestine within one hour.

Chemical Properties

Off-White Waxy Solid (low-melting)

Uses

The unusual sugar Tyvelose is the immunodominant portion of the major larval glycoprotein antigens of Trichinella spiralis, which play an important role in generating immunity against the intestinal stages of infection.

Definition

ChEBI: Tyvelose is a deoxymannose.

tyvelose Preparation Products And Raw materials

Raw materials

Preparation Products

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tyvelose 3,6-Dideoxy-D-mannose D-Tyvelose 3,6-Dideoxy- D-arabino-Hexose, 3,6-dideoxy- 5658-12-8 12/8/5658 5658-16-8 13C & 2H Sugars Carbohydrates & Derivatives Intermediates & Fine Chemicals Pharmaceuticals