N,N-dimethylarginine
- CAS No.
- 30315-93-6
- Chemical Name:
- N,N-dimethylarginine
- Synonyms
- ArginineImpurity12;H-Arg(NMe2)-OH(asym);N,N-dimethylarginine;Asymmetric dimethylarginine;L-Arg(Me,Me)-OH(asymmetrical), >97%;N(omega),N(omega)-dimethyl-L-arginine;L-Ornithine, N5-[(dimethylamino)iminomethyl]-;Arginine Impurity 12（N, N-Dimethyl-L-Arginine）;N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%;(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid
- CBNumber:
- CB21351907
- Molecular Formula:
- C8H18N4O2
- Molecular Weight:
- 202.25
- MDL Number:
- MFCD00038406
- MOL File:
- 30315-93-6.mol
- MSDS File:
- SDS
| Boiling point | 340.8±52.0 °C(Predicted) |
|---|---|
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): freely soluble |
| form | A crystalline solid |
| pka | 2.50±0.24(Predicted) |
| FDA UNII | 63CV1GEK3Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
N,N-dimethylarginine price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00938 | Dimethyl-L-arginine ≥95% (HPLC) | 30315-93-6 | 100MG | $210 | 2024-03-01 | Buy |
| Sigma-Aldrich | SMB00938 | Dimethyl-L-arginine ≥95%(HPLC) | 30315-93-6 | 500MG | $524 | 2024-03-01 | Buy |
| ChemScene | CS-0059330 | Asymmetricdimethylarginine >98.0% | 30315-93-6 | 1g | $495 | 2021-12-16 | Buy |
| ChemScene | CS-0059330 | Asymmetricdimethylarginine >98.0% | 30315-93-6 | 250mg | $195 | 2021-12-16 | Buy |
| ChemScene | CS-0059330 | Asymmetricdimethylarginine >98.0% | 30315-93-6 | 5g | $1485 | 2021-12-16 | Buy |
N,N-dimethylarginine Chemical Properties,Uses,Production
Uses
Metabolomics
Definition
ChEBI: A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.
General Description
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma.
N,N-dimethylarginine Preparation Products And Raw materials
Raw materials
Preparation Products
N,N-dimethylarginine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |