STIRIPENTOL
- CAS No.
- 49763-96-4
- Chemical Name:
- STIRIPENTOL
- Synonyms
- Diacomit;bcx2600;RCX-2600;STIRIPENTOL;Stiripentol >Stiripentol(BCX 2600);STIRIPENTOL USP/EP/BP;Z-alpha-Methylcinnamaldehyde;1-(1,3-BENZODIOXOL-5YL)-4,4-DIMETHYL-1-PENTEN-3-OL;1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-o
- CBNumber:
- CB2150457
- Molecular Formula:
- C14H18O3
- Molecular Weight:
- 234.29
- MDL Number:
- MFCD00869310
- MOL File:
- 49763-96-4.mol
Melting point | 73-74°C |
---|---|
Boiling point | 365.4±11.0 °C(Predicted) |
Density | 1.139±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO: ≥20mg/mL |
pka | 14.45±0.20(Predicted) |
form | powder |
color | white to beige |
InChIKey | IBLNKMRFIPWSOY-FNORWQNLSA-N |
CAS DataBase Reference | 49763-96-4 |
FDA UNII | R02XOT8V8I |
ATC code | N03AX17 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P280-P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | SB3393000 | |||||||||
HS Code | 2932.99.7000 | |||||||||
NFPA 704 |
|
STIRIPENTOL price More Price(49)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S6826 | Stiripentol ≥98% (HPLC) | 49763-96-4 | 5mg | $87.5 | 2024-03-01 | Buy |
Sigma-Aldrich | S6826 | Stiripentol ≥98% (HPLC) | 49763-96-4 | 25mg | $354 | 2024-03-01 | Buy |
TCI Chemical | S0905 | Stiripentol >98.0%(GC) | 49763-96-4 | 1g | $245 | 2024-03-01 | Buy |
TCI Chemical | S0905 | Stiripentol >98.0%(GC) | 49763-96-4 | 5g | $846 | 2024-03-01 | Buy |
Cayman Chemical | 17781 | Stiripentol ≥98% | 49763-96-4 | 5mg | $68 | 2024-03-01 | Buy |
STIRIPENTOL Chemical Properties,Uses,Production
Description
Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing α3 subunits and to a lower extent in those containing β1 or ε subunits. It also inhibits GABA reuptake in vitro and increases the release of GABA in neonatal rat hippocampal slices. Stiripentol (500 μM) inhibits lactate dehydrogenase (LDH), blocking both lactate-to-pyruvate and pyruvate-to-lactate conversions by human LDH1 and LDH5. Formulations containing stiripentol have been used in the adjunctive treatment of seizures associated with Dravet syndrome.
Chemical Properties
White Solid
Uses
Stiripentol has been used in pharmacokinetic analysis and as a reference standard in fluorescence spectra analysis.
Uses
An antiepileptic drug
Uses
Stiripentol is an epilepsy drug, it has been used as co-therapy for treatment of epilepsy.
Definition
ChEBI: 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol is a phenylpropanoid.
Biochem/physiol Actions
Anti-convulsant drug
STIRIPENTOL Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21700 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12321 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17368 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from STIRIPENTOL manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-01-20 | Stiripentol
49763-96-4
|
US $9.90-1277.00 / g | 10g | 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customized packaging | 100KG/Month | Wuhan Biocar Pharmacy Co., Ltd. | ||
2021-11-02 | STIRIPENTOL
49763-96-4
|
US $714.30 / Kg/Bag | 1KG | 99% | 500kg | Baoji Guokang Healthchem co.,ltd | ||
2021-08-18 | STIRIPENTOL USP/EP/BP
49763-96-4
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
- Stiripentol
49763-96-4
- US $9.90-1277.00 / g
- 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customized packaging
- Wuhan Biocar Pharmacy Co., Ltd.
- STIRIPENTOL
49763-96-4
- US $714.30 / Kg/Bag
- 99%
- Baoji Guokang Healthchem co.,ltd
- STIRIPENTOL USP/EP/BP
49763-96-4
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited