ChemicalBook >> CAS DataBase List >>H-1152Glycyl, Dihydrochloride
H-1152Glycyl, Dihydrochloride
- CAS No.
- 913844-45-8
- Chemical Name:
- H-1152Glycyl, Dihydrochloride
- Synonyms
- Glycyl-H 1152 2HCl;Rho Kinase Inhibitor IV;Glycyl H-1152 hydrochloride;H-1152Glycyl, Dihydrochloride;(S)-Glycyl-H-1152 (hydrochloride);Glycyl H1152 hydrochloride,Glycyl H 1152 hydrochloride;(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride;(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride;2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride
- CBNumber:
- CB21564868
- Molecular Formula:
- C18H26Cl2N4O3S
- Molecular Weight:
- 0
- MDL Number:
- MFCD09971082
- MOL File:
- 913844-45-8.mol
Last updated:2023-06-30 15:45:59
| Melting point | 190-192°C |
|---|---|
| storage temp. | Refrigerator |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | Pale Yellow to Beige |
| Stability | Hygroscopic |
| CAS DataBase Reference | 913844-45-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H370 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P260-P264-P270-P280-P303+P361+P353-P307+P311-P321-P370+P378-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
H-1152Glycyl, Dihydrochloride price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 13332 | (S)-Glycyl-H-1152 (hydrochloride) ≥98% | 913844-45-8 | 500μg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 13332 | (S)-Glycyl-H-1152 (hydrochloride) ≥98% | 913844-45-8 | 1mg | $176 | 2024-03-01 | Buy |
| Cayman Chemical | 13332 | (S)-Glycyl-H-1152 (hydrochloride) ≥98% | 913844-45-8 | 5mg | $728 | 2024-03-01 | Buy |
| Cayman Chemical | 13332 | (S)-Glycyl-H-1152 (hydrochloride) ≥98% | 913844-45-8 | 10mg | $1274 | 2024-03-01 | Buy |
| Usbiological | 013030 | H-1152 Glycyl Dihydrochloride | 913844-45-8 | 1mg | $460 | 2021-12-16 | Buy |
H-1152Glycyl, Dihydrochloride Chemical Properties,Uses,Production
Chemical Properties
Pale-Yellow Solid
Uses
A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.
Biological Activity
Glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride ((S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride ) that displays improved ROCKII selectivity. IC 50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μ M for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.
storage
room temperature (desiccate)
H-1152Glycyl, Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
H-1152Glycyl, Dihydrochloride Suppliers
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Hangzhou Yuhao Chemical Technology Co., Ltd | 0571-82693216 | info@yuhaochemical.com | China | 9394 | 52 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| HUNAN CHEMFISH SCIENTIFIC CO.,LTD | +86-0731-85567275 13021512891 | sales02@chemfish.com | China | 6581 | 58 |
913844-45-8(H-1152Glycyl, Dihydrochloride)Related Search:
(2S)-4-(Aminoacetyl)hexahydro -2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride
2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride
(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl) sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
(S)-Glycyl-H-1152 (hydrochloride)
Glycyl-H 1152 2HCl
Rho Kinase Inhibitor IV
H-1152Glycyl, Dihydrochloride
Glycyl H-1152 hydrochloride
Glycyl H1152 hydrochloride,Glycyl H 1152 hydrochloride
913844-45-8
C18H26Cl2N4O3S
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