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BOC-D-THR-OH

BOC-D-THR-OH Structure
BOC-D-THR-OH structure
CAS No.
55674-67-4
Chemical Name:
BOC-D-THR-OH
Synonyms
BOC-D-THR;BOC-D-THR-OH;BOC-D-THREONINE;N-Boc-L-threonine;BOC-D-THR-OH USP/EP/BP;BOC-D-THREONINE extrapure;N-ALPHA-T-BOC-D-THREONINE;Boc-D-threonine≥ 98% (HPLC);BOC-D-Threonine(BOC-D-Thr-OH);N-Boc-D-threonine Boc-D-Thr-OH
CBNumber:
CB2177386
Molecular Formula:
C9H17NO5
Molecular Weight:
219.24
MDL Number:
MFCD00037807
MOL File:
55674-67-4.mol
Last updated:2026-01-13 11:16:32
Product description Number Pack Size Price
Boc-D-Thr-OH Novabiochem® 8.53102 5 g $63
Boc-D-Thr-OH Novabiochem® 8.53102 25 g $628
N-(tert-Butoxycarbonyl)-D-threonine >98.0%(HPLC)(T) B2990 5g $335
N-Boc-D-threonine B668000 1g $55
Boc-D-threonine 264831 5g $360
More product size
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BOC-D-THR-OH Properties

Melting point 81 °C
refractive index 9 ° (C=1, AcOH)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Solid
color White to Almost white
Water Solubility Slightly soluble in water.
Major Application peptide synthesis
InChI 1S/C9H17NO5/c1-5(11)6(7(12)13)10-8(14)15-9(2,3)4/h5-6,11H,1-4H3,(H,10,14)(H,12,13)/t5-,6+/m0/s1
InChIKey LLHOYOCAAURYRL-NTSWFWBYSA-N
SMILES N([C@H]([C@@H](O)C)C(=O)O)C(=O)OC(C)(C)C
CAS DataBase Reference 55674-67-4(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  WGK 1
HS Code  29225090
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

BOC-D-THR-OH price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.53102 Boc-D-Thr-OH Novabiochem® 55674-67-4 5 g $63 2025-07-31 Buy
Sigma-Aldrich 8.53102 Boc-D-Thr-OH Novabiochem® 55674-67-4 25 g $628 2025-07-31 Buy
TCI Chemical B2990 N-(tert-Butoxycarbonyl)-D-threonine >98.0%(HPLC)(T) 55674-67-4 5g $335 2025-07-31 Buy
TRC B668000 N-Boc-D-threonine 55674-67-4 1g $55 2021-12-16 Buy
Usbiological 264831 Boc-D-threonine 55674-67-4 5g $360 2021-12-16 Buy
Product number Packaging Price Buy
8.53102 5 g $63 Buy
8.53102 25 g $628 Buy
B2990 5g $335 Buy
B668000 1g $55 Buy
264831 5g $360 Buy

BOC-D-THR-OH Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

It is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. Also used as a synthetic intermediate for the production of chiral antibiotics.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

L(+)-allo-Threonine

28954-12-3

Di-tert-butyl dicarbonate

24424-99-5

Boc-L-Threonine

2592-18-9

The general procedure for the synthesis of (2S,3R)-2-((tert-butoxycarbonyl)amino)-3-hydroxybutyric acid from (2S,3S)-2-amino-3-hydroxybutyric acid and di-tert-butyl dicarbonate is as follows: 1. di-tert-butyl dicarbonate (550 mg, 2.52 mmol) was added to a mixture of methanol (2.5 mL) and water (2.5 mL) containing L-isothreonine (250 mg, 2.10 mmol) and sodium bicarbonate (529 mg, 6.30 mmol) at 0 °C. 2. The reaction mixture was gradually warmed to room temperature and stirred continuously at room temperature for 18 hours. 3. Upon completion of the reaction, the methanol was removed by concentration and the remaining aqueous phase was adjusted to pH 3~4 with 6N hydrochloric acid solution. 4. The acidified aqueous phase was extracted with ether (3 times) and all organic phases were combined. 5. The organic phase was washed with water and brine sequentially, and then dried with anhydrous sodium sulfate. 6. The desiccant was removed by filtration, and the filtrate was concentrated under vacuum and further dried under vacuum for 24 h. (2R,3S)-2-((tert-butoxycarbonyl)amino)-3-hydroxybutyric acid (304 mg) was obtained as a white solid. Product identification: LCMS retention time (Rt) = 0.36 min; mass spectrum (MS) m/z 220 [M + H]+, m/z 218 [M-H]-.

References

[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 38, p. 6935 - 6960
[2] Journal of the American Chemical Society, 2000, vol. 122, # 41, p. 10214 - 10215
[3] Journal of the American Chemical Society, 2003, vol. 125, # 7, p. 1877 - 1887
[4] Journal of Organic Chemistry, 1982, vol. 47, # 26, p. 5160 - 5167
[5] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 16, p. 4329 - 4332

BOC-D-THR-OH Preparation Products And Raw materials

Raw materials

L(+)-allo-Threonine Di-tert-butyl dicarbonate Sodium bicarbonate Methanol Water

Preparation Products

BOC-D-THR-OH Suppliers

Global( 171)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		+8617390183901 cynthia@enlaibio.com China 1098 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29830 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Supplier Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
GenicBio Limited 		58
career henan chemical co 		58
Accela ChemBio Inc. 		58
Hubei xin bonus chemical co. LTD 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from BOC-D-THR-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-D-Thr-OH pictures 2026-03-05 Boc-D-Thr-OH
55674-67-4
 US $0.00-0.00 / kg 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
BOC-D-THR-OH pictures 2019-07-06 BOC-D-THR-OH
55674-67-4
 US $1.00 / kg 1kg 95%-99% as request Career Henan Chemical Co
  • Boc-D-Thr-OH pictures
  • Boc-D-Thr-OH
    55674-67-4
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • BOC-D-THR-OH pictures
  • BOC-D-THR-OH
    55674-67-4
  • US $1.00 / kg
  • 95%-99%
  • Career Henan Chemical Co

BOC-D-THR-OH Spectrum

BOC-D-THR-OH(55674-67-4)MSBOC-D-THR-OH(55674-67-4)1HNMRBOC-D-THR-OH(55674-67-4)IR1

55674-67-4(BOC-D-THR-OH)Related Search:

Boc-Thr(Bzl)-OH N-(tert-Butoxycarbonyl)-O-benzyl-D-threonine BOC-D-THR-OH BOC-L-THR-OH D-Threonine
(R,S)-A-N-BOC-AMINO-B-HYDROXY-CYCLOHEXANEPROPANIC ACID N-BOC-(R)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID BOC-D-THR(TBU)-OH BOC-D-THREO-3-(FURAN-2-YL)SERINE BOC-D-THREO-3-(PYRIDIN-2-YL)SERINE
BOC-D-THREO-3-PHENYLSERINE BOC-(2R,3S)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID BOC-D-THREO-3-(THIOPHEN-2-YL)SERINE BOC-CIS-3-HYDROXY-D-PROLINE Boc-allo-Thr-OH,BOC-ALLO-THR-OH DCHA
BOC-D-THR(BZL)-O-CH2-PHI-CH2-COOH DCHA methyl (2R,3S)-2-[(tert-butoxycarbonyl)amino]-3-hydroxy-3-(2-nitrophenyl)propanoate methyl (2R,3S)-2-[(tert-butoxycarbonyl)amino]-3-hydroxy-3-(3-nitrophenyl)propanoate

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N-ALPHA-TERT-BUTOXYCARBONYL-D-THREONINE N-ALPHA-T-BUTOXYCARBONYL-D-THREONINE N-ALPHA-T-BOC-D-THREONINE N-ALPHA-T-BOC-D-THREONINE / (2R,3S) N-TERT-BUTOXYCARBONYL-D-THREONINE BOC-D-THR-OH BOC-D-THREONINE BOC-D-THR BOC-D-THREONINE extrapure N-Boc-L-threonine BOC-D-Threonine(BOC-D-Thr-OH) N-Boc-D-threonine Boc-D-Thr-OH (2R,3S)-2-((tert-Butoxycarbonyl)aMino)-3-hydroxybutanoic acid Boc-D-threonine≥ 98% (HPLC) (Tert-Butoxy)Carbonyl D-Thr-OH (2R,3S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid N-(tert-Butoxycarbonyl)-D-threonine > D-Threonine, N-[(1,1-dimethylethoxy)carbonyl]- BOC-D-THR-OH USP/EP/BP 55674-67-4 Threonine [Thr, T] Boc-Amino Acids and Derivative Amino Acids Amino Acids (N-Protected) Biochemistry Boc-Amino Acids