ChemicalBook >> CAS DataBase List >>4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] structure

CAS No.: 27470-51-5

Chemical Name:: 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

Synonyms: ae-17;flogos;alfide;solurol;Aflogan;Calibene;SUXIBUZONE;Suxibuzona;lidinedione;Suxibuzonum

CBNumber:: CB2196749

Molecular Formula:: C24H26N2O6

Molecular Weight:: 438.47

MDL Number:: MFCD00079562

MOL File:: 27470-51-5.mol

Last updated:2023-05-18 11:31:00

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4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Properties

Melting point	126-127°
Boiling point	550.33°C (rough estimate)
Density	1.2847 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	2-8°C
solubility	Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
pka	4.33±0.17(Predicted)
color	White to Off-White
CAS DataBase Reference	27470-51-5
FDA UNII	86TDZ5WP2B
ATC code	M02AA22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332
Precautionary statements	P261-P280-P301+P312+P330
Hazard Codes	Xn
Risk Statements	20/21/22
Safety Statements	36
WGK Germany	3
RTECS	WM9640000
Toxicity	LD50 orally in mice: 5.683 micromol/kg (Esteve, 1973)

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S2400000	Suxibuzone European Pharmacopoeia (EP) Reference Standard	27470-51-5	s2400000	$220	2024-03-01	Buy
TRC	S880000	Suxibuzone	27470-51-5	100mg	$80	2021-12-16	Buy
AK Scientific	X6836	Suxibuzone	27470-51-5	100mg	$89	2021-12-16	Buy
American Custom Chemicals Corporation	API0008442	SUXIBUZONE 95.00%	27470-51-5	100MG	$238.35	2021-12-16	Buy
Medical Isotopes, Inc.	48782	Suxibuzone	27470-51-5	5G	$2200	2021-12-16	Buy

Product number	Packaging	Price	Buy
S2400000	s2400000	$220	Buy
S880000	100mg	$80	Buy
X6836	100mg	$89	Buy
API0008442	100MG	$238.35	Buy
48782	5G	$2200	Buy

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone. It is a drug used for joint and muscular pain.

Uses

analgesic, antipyretic, antiinflammatory

Definition

ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.

brand name

Calibene;Danalon om;Danilon;Flamilon;Flofos.

World Health Organization (WHO)

Suxibuzone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1974 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone.

Biochem/physiol Actions

A prodrug of phenylbutazone.

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Preparation Products And Raw materials

Raw materials

Preparation Products

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Suppliers

Global( 82)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19639	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Nextpeptide Inc	58
Alfa Chemistry	58
Coresyn Pharmatech Co., Ltd.	58
Aceschem Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

27470-51-5(4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER])Related Search:

3-METHOXYPROPIONIC ACID HYDRAZIDE 4,4-Dimethyl-1-phenyl-3-pyrazolidone 1-Acetyl-2-phenylhydrazine MOFEBUTAZONE 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

Dimezone S 3-AMINO-2,2-DIMETHYL-1-PROPANOL 1,2-Diphenylhydrazine Phenylbutazone Phenidone

1-Phenyl-4-methyl-3-pyrazolidone 2,2-Dimethylpropionic acid hydrazide 1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE 2,2,2-TRIMETHYLACETANILIDE 3-METHOXY-2,2-DIMETHYLPROPYLAMINE

MALONANILIDE N-PHENYL-N'-PROPIONYLHYDRAZINE 2,2-dimethyl-3-(methylamino)propan-1-ol

1of4

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 4-butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedio 4-butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedionehydrogensuccinate ae-17 alfide SUXIBUZONE butanedioicacid,mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl flogos lidinedione solurol succinicacid,monoesterwith4-butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazo 3-(1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine-4-ylmethoxycarbonyl)propionic acid Succinic acid hydrogen (1,2-diphenyl-3,5-dioxo-4-butylpyrazolidin-4-yl)methyl ester Succinic acid hydrogen (4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl ester Succinic acid hydrogen 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester 3-((4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxycarbonyl)propionsaeure 3,5-Pyrazolidinedione, 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-, hydrogen succinate (ester) 4-Butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione 4-Hydroxymethylbutazolidine hemisuccinate Aflogan Acetanilide Impurity 1 Suxibuzone CRS Butanedioic acid, 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester 4-((4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy)-4-oxobutanoic acid Calibene Suxibuzona Suxibuzonum Inhibitor,Suxibuzone,inhibit 1-[3-[2-(dimethylamino)ethyl]-1-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfon amide 27470-51-5 Biochemicals and Reagents BioChemical Substrate Analogs Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Enzyme Inhibitors DANILON