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Cefotaxime sodium

Brand Name(s) in US
Cefotaxime sodium
Cefotaxime sodium structure
CAS No.
64485-93-4
Chemical Name:
Cefotaxime sodium
Synonyms
ctx;hr756;Pretor;ru24756;Cefotax;Chemcef;Tolycar;FIR-756;CLAFORAN;Cefotaxime Na
CBNumber:
CB2197478
Molecular Formula:
C16H16N5NaO7S2
Formula Weight:
477.45
MOL File:
64485-93-4.mol

Cefotaxime sodium Properties

Melting point:
162-163 C
alpha 
D20 +55±2° (c = 0.8 in water)
refractive index 
61 ° (C=1, H2O)
storage temp. 
2-8°C
solubility 
H2O: aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.soluble
form 
powder
color 
white to yellow
PH
pH(100g/l, 25℃) : 4.5~6.5
Water Solubility 
Soluble in water.
Merck 
14,1933
BRN 
5711411
Stability:
Stable. Incompatible with strong oxidizing agents.
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  42/43
Safety Statements  22-36/37-60-45-37-24
WGK Germany  2
RTECS  XI0250000
HS Code  29419000
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Cefotaxime sodium price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C7039 Cefotaxime sodium salt plant cell culture tested, BioReagent, powder 64485-93-4 1g $220 2018-11-13 Buy
Sigma-Aldrich 1097909 Cefotaxime sodium United States Pharmacopeia (USP) Reference Standard 64485-93-4 500mg $352.8 2018-11-20 Buy
Alfa Aesar J62690 Cefotaxime sodium salt 64485-93-4 1g $78.7 2018-11-13 Buy
Alfa Aesar J62690 Cefotaxime sodium salt 64485-93-4 5g $163 2018-11-13 Buy
Cayman Chemical 16040 Cefotaxime (sodium salt) ≥98% 64485-93-4 1g $60 2018-11-13 Buy

Cefotaxime sodium Chemical Properties,Uses,Production

Brand Name(s) in US

Claforan

Chemical Properties

White to pale yellow crystalline powder

Uses

Cephalosporin antibacterial

Uses

Broad spectrum third generation cephalosporin antibiotic. The name Cefotaxime applies to the isomer having a syn-methoxy imino group

Definition

ChEBI: A cephalosporin organic sodium salt having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups.

brand name

Claforan (Sanofi Aventis).

Clinical Use

Cefotaxime (Claforan) was the first third-generationcephalosporin to be introduced. It possesses excellentbroad-spectrum activity against Gram-positive and Gramnegativeaerobic and anaerobic bacteria. It is more activethan moxalactam against Gram-positive organisms. Manyβ-lactamase–producing bacterial strains are sensitive to cefotaxime,including N. gonorrhoeae, Klebsiella spp., H. influenzae,S. aureus, and E. cloacae. Some, but not all,Pseudomonas strains are sensitive. Enterococci and Listeriamonocytogenes are resistant.
The syn-isomer of cefotaxime is significantly more activethan the anti-isomer against β-lactamase–producing bacteria.This potency difference is, in part, because of greaterresistance of the syn-isomer to the action of β-lactamases.The higher affinity of the syn-isomer for PBPs, however,may also be a factor.
Cefotaxime is metabolized in part to the less active desacetylmetabolite. Approximately 20% of the metaboliteand 25% of the parent drug are excreted in the urine. Theparent drug reaches the cerebrospinal fluid in sufficient concentrationto be effective in the treatment of meningitis.Solutions of cefotaxime sodium should be used within 24hours. If stored, they should be refrigerated. Refrigerated solutionsmaintain potency up to 10 days.

Cefotaxime sodium Preparation Products And Raw materials

Raw materials

Preparation Products


Cefotaxime sodium Suppliers

Global( 317)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 500 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2548 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20243 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8430 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 295 58

View Lastest Price from Cefotaxime sodium manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-09-21 Pharmaceutical Raw Material Cefotaxime Sodium Cas:64485-93-4
64485-93-4
US $10.00 / G 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.

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