RICININE
- CAS No.
- 524-40-3
- Chemical Name:
- RICININE
- Synonyms
- ricinin;Ricidine;RICININE;Ritsinin;recinine;NSC 642604;NSC 409913;Ricinine (6CI);Ricinine solution;2-keto-4-methoxy-1-methyl-nicotinonitrile
- CBNumber:
- CB2202950
- Molecular Formula:
- C8H8N2O2
- Molecular Weight:
- 164.16
- MDL Number:
- MFCD00171320
- MOL File:
- 524-40-3.mol
| Melting point | 201.5° |
|---|---|
| Boiling point | 291.62°C (rough estimate) |
| Density | 1.2739 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| Flash point | 2℃ |
| storage temp. | -20°C |
| solubility | DMSO: slightly soluble,Methanol: slightly soluble |
| form | A solid |
| pka | -4.93±0.62(Predicted) |
| Water Solubility | 2.7g/L(10 ºC) |
| CAS DataBase Reference | 524-40-3 |
| FDA UNII | 130UFS7AE0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | T,Xn,F | |||||||||
| Risk Statements | 25-36-20/21/22-11 | |||||||||
| Safety Statements | 45-36/37-16 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QT3100000 | |||||||||
| NFPA 704 |
|
RICININE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00079 | Ricinine ≥95% (LC/MS-ELSD) | 524-40-3 | 1mg | $320 | 2024-03-01 | Buy |
| Usbiological | 020655 | Ricinine | 524-40-3 | 100mg | $460 | 2021-12-16 | Buy |
| TRC | R495550 | Ricinine | 524-40-3 | 500mg | $835 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0002136 | RICININE 95.00% | 524-40-3 | 5MG | $345.4 | 2021-12-16 | Buy |
| AHH | MT-22192 | Ricinine 98% | 524-40-3 | 0.1g | $345 | 2021-12-16 | Buy |
RICININE Chemical Properties,Uses,Production
Description
First isolated by Tuson from the seeds of Ricinus communis (castor-oil seed), the alkaloid was subsequently examined by Soave, Schultze and Evans. The base crystallizes from H20 in colourless prisms or leaflets and sublimes at 170-lS0°C/ 20 mm. It is soluble in hot H20 or CHCI3, only sparingly so in EtOH and insoluble in petroleum ether, is neutral in reaction, optically inactive and forms no normal salts although the mercurichloride, m.p. 204°C has been prepared. The alkaloid reduces KMn04 and may be hydrolyzed by alkalies to MeOH and ricininic acid which forms brilliant, slender needles, m.p. 296-8°C (dec.). The structure of ricinine has been confirmed by synthesis from 4-chloroquinoline. Other syntheses have also been achieved. The base is not particularly toxic and the poisonous character of castor-oil seeds has been shown to be due to a more complex substance, ricin, the toxicity of which may be destroyed by heating.
Chemical Properties
White Solid
Uses
Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. Ricinine also has bactericidal effects on three pests and heptaprotective activity.
Uses
An alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). It is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. It also has bactericidal effects on t
Definition
ChEBI: Ricinine is a pyridine alkaloid, a pyridone and a nitrile.
Hazard
Toxic by ingestion.
Safety Profile
A poison by ingestion and subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.
References
Tuson.,J. Chern. Soc., 17,195 (1864)
Soave., Chern. Soc. Abstr., i, 386 (1896)
Schultze., ibid, i, 42 (1898)
Evans., J. Arner. Chern. Soc., 22, 39 (1900)
Maqueen, Philippe., Cornpt. rend., 138, 506 (1904)
Maqueen, Philippe., ibid, 139, 840 (1904)
Winterstein, Keller, Weinhagen., Arch. Pharrn., 255,513 (1917)
Bottcher., Ber., 51,673 (1918)
Spath, Tschelnitz., Monatsh., 42,251 (1921)
Spath, Koller., Ber., 56, 880, 2454 (1923)
Spath, Koller., ibid, 58,2124 (1925)
Schroeter et ai., ibid, 65, 432 (1932)
Reitmann., Chern. Abstr., 29,4359 (1935)
RICININE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4515 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 9174 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9288 | 58 |