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N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester Structure
N-Boc-trans-4-Hydroxy-L-proline methyl ester structure
CAS No.
74844-91-0
Chemical Name:
N-Boc-trans-4-Hydroxy-L-proline methyl ester
Synonyms
1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;BOC-HYP-OME;Boc-L-Hyp-OMe;N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER;1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;GOSO-001;BOC-L-Hyp Methyl ester;BOC-HYDROXYPROLINE-OME;N-Boc-trans-4-hydroxy-L;(Tert-Butoxy)Carbonyl Hyp-OMe
CBNumber:
CB2207339
Molecular Formula:
C11H19NO5
Molecular Weight:
245.27
MDL Number:
MFCD00076981
MOL File:
74844-91-0.mol
MSDS File:
SDS
Last updated:2024-03-28 13:39:29
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N-Boc-trans-4-Hydroxy-L-proline methyl ester Properties

Melting point 92-96 °C (lit.)
alpha -65 º (c=1 CHCl3)
Boiling point 132°C/0.05mmHg(lit.)
Density 1.216±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in chloroform, dichloromethane and ethyl acetate.
form Crystalline Powder
pka 14.27±0.40(Predicted)
color White to light beige
optical activity [α]20/D -65°, c = 1% in chloroform
InChI InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@H]1C(OC)=O
LogP 0.813 at 25℃
CAS DataBase Reference 74844-91-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P301+P330+P331-P304+P340+P310-P305+P351+P338+P310
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

N-Boc-trans-4-Hydroxy-L-proline methyl ester price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 639737 N-Boc-trans-4-hydroxy-L-proline methyl ester 97% 74844-91-0 5g $26 2024-03-01 Buy
TCI Chemical B3843 N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester >95.0%(GC) 74844-91-0 1g $33 2024-03-01 Buy
TCI Chemical B3843 N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester >95.0%(GC) 74844-91-0 5g $97 2024-03-01 Buy
Alfa Aesar H59027 N-Boc-trans-4-hydroxy-L-proline methyl ester, 97% 74844-91-0 1g $30.65 2024-03-01 Buy
Alfa Aesar H59027 N-Boc-trans-4-hydroxy-L-proline methyl ester, 97% 74844-91-0 5g $99.65 2024-03-01 Buy
Product number Packaging Price Buy
639737 5g $26 Buy
B3843 1g $33 Buy
B3843 5g $97 Buy
H59027 1g $30.65 Buy
H59027 5g $99.65 Buy

N-Boc-trans-4-Hydroxy-L-proline methyl ester Chemical Properties,Uses,Production

Chemical Properties

Clear Colourless Oil

Uses

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

Uses

(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester roline scaffold.

Uses

A potential iNOS inhibitor.

N-Boc-trans-4-Hydroxy-L-proline methyl ester synthesis

13726-69-7
18107-18-1
74844-91-0
Synthesis of N-Boc-trans-4-Hydroxy-L-proline methyl ester from Boc-Hyp-OH and (TRIMETHYLSILYL)DIAZOMETHANE

N-Boc-trans-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials

Raw materials

trans-4-Hydroxy-L-proline methyl ester hydrochloride (2S,4R)-1-tert-butyl 2-Methyl 4-((tert-butyldiMethylsilyl)oxy)-5-oxopyrrolidine-1,2-dicarboxylate Boc-Hyp-OH Trans-4-Hydroxy-L-proline Hydrochloride (S)-N-Boc-allylglycine
TRANS-4-HYDROXY-L-PROLINE METHYL ESTER (TRIMETHYLSILYL)DIAZOMETHANE tert-butyl azidoformate L-Hydroxyproline

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Preparation Products

N-Boc-4-oxo-L-Proline methyl ester 2-PyrrolidineMethanol, 4-hydroxy-, hydrochloride (1:1), (2S,4R)- (S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide 1-Boc-(2S,4S)-2-cyano-4-fluoropyrrolidine N-BOC-cis-4-fluoro-L-proline
(2S,4S)-1-tert-butyl 2-methyl 4-chloropyrrolidine-1,2-dicarboxylate (2S,4R)-1-BOC-4-BENZYLOXY-PYRROLIDINE-2-DICARBOXYLIC ACID METHYL ESTER

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N-Boc-trans-4-Hydroxy-L-proline methyl ester Suppliers

Global( 445)Suppliers
Supplier Tel Email Country ProdList Advantage
PRISUN PHARMATECH CO.,LTD
+86-021-54326183-8001 +8618917565227 prisun@prisunpharma.com China 215 58
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd
+86-86-13383293380 +8613230482270 1919301810@qq.com China 141 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		0523-86132544 sales@thbiochem.com CHINA 305 60
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Supplier Advantage
PRISUN PHARMATECH CO.,LTD
58
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd
58
Hebei Yanxi Chemical Co., Ltd. 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Taizhou Tianhong Biochemistry Technology Co., Ltd. 		60
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55

View Lastest Price from N-Boc-trans-4-Hydroxy-L-proline methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Boc-trans-4-Hydroxy-L-proline methyl ester pictures 2024-03-29 N-Boc-trans-4-Hydroxy-L-proline methyl ester
74844-91-0
 US $6.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
N-Boc-trans-4-Hydroxy-L-proline methyl ester pictures 2024-01-02 N-Boc-trans-4-Hydroxy-L-proline methyl ester
74844-91-0
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
N-Boc-trans-4-Hydroxy-L-proline methyl ester pictures 2023-11-29 N-Boc-trans-4-Hydroxy-L-proline methyl ester
74844-91-0
 US $20.00-1.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.

N-Boc-trans-4-Hydroxy-L-proline methyl ester Spectrum

N-Boc-trans-4-Hydroxy-L-proline methyl ester(74844-91-0)1HNMRN-Boc-trans-4-Hydroxy-L-proline methyl ester(74844-91-0)IR

74844-91-0(N-Boc-trans-4-Hydroxy-L-proline methyl ester)Related Search:

Tribenuron methyl Basic Violet 1 L-PROLINE-(4-3H(N)) CHLOROPHOSPHONAZO III Methylparaben
BOC-L-Proline D-Proline L-Hydroxyproline Methyl salicylate cis-4-Hydroxy-L-proline
Methanol Kresoxim-methyl Methyl acrylate N-Boc-trans-4-tosyloxy-L-proline methyl ester N-Boc-trans-4-amino-L-proline methyl ester hydrochloride
N-Boc-trans-4-amino-L-proline methyl ester Methyl 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

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N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER N-(TERT-BUTOXYCARBONYL)-TRANS-HYDROXYL-L-PROLINE METHYL ESTER N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER (2R,4R)-4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER (2S,4R)-1-(TERT-BUTOXYCARBONYL)-2-CARBOMETHOXY-4-HYDROXYPYRROLIDINE (2S,4R)-BOC 4-HYDROXYPROLINE METHYL ESTER (2S,4R)-1-BOC-4-hydroxy pyrrolidine-2-carboxylic acid methyl ester (2S,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(methoxycarbonyl)pyrrolidine, trans-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline methyl ester 1-(tert-butyl) 2-Methyl (2S,4R)-4-hydroxytetrahydro-1H-pyrrole-1,2-dicarboxylate (2S,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate 1-(tert-butyl) 2-Methyl (2S,4R)-4-hydro×ytetrahydro-1H-pyrrole-1,2-dicarbo×ylate N-Boc-trans-4-hydroxy-L-proline Methyl Ester trans-Boc-Hyp-OMe 1-tert-Butyl 2-Methyl (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylate (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4R)- N-Boc-trans-4-hydroxy-L-proline methyl ester 97% N-BOC-L-Hydroxyproline methyl ester BOC-L-Hyp Methyl ester trans-N-Boc-4-hydroxy-L-proline Methyl Ester N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline methyl ester BOC-L-4-HYDROXYPROLINE METHYL ESTER BOC-HYDROXYPROLINE-OME BOC-L-T-4-HYDROXYPROLINE METHYL ESTER BOC-L-HYDROXYPROLINE METHYL ESTER BOC-L-4-TRANS-HYDROXYPROLINE METHYL ESTER BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL & N-Boc-trans-hydro-L-prolinemethylester N-tert-Butoxycarbonyl-trans-4-hydroxy-L-proline methyl ester N-(tert-Butoxycarbonyl)-trans-hydroxy-L-proline methyl ester (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester Methyl (4R)-N-Boc-4-hydroxy-L-prolinate N-tert-Butoxycarbonyl-L-hydroxyproline Methyl Ester BOC-HYP-OME / BOC-L-HYDROXYPROLINE METHYL ESTER N-BOC-trans-4-Hydroxy-L-proline methyl ester,97% N-BOC-transydro-L-prolinemethylester Boc-L-4-trans-hydroxyproline methyl ester≥ 99% (HPLC, Chiral purity) trans-N-Boc-4-hydroxy-L-proline Methyl Ester,99%e.e. 1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate O1-tert-Butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate (2S,4R)-N-Boc-trans-4-hydroxy-L-proline methyl ester (Tert-Butoxy)Carbonyl Hyp-OMe GOSO-001 (2S,4R)-N-Boc-4-hydroxyproline methyl ester N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester > N-Boc-trans-4-hydroxy-L (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER,74844-91-0 N-Boc-trans-4-Hydroxy-L-proline methyl ester USP/EP/BP Tert butoxycarbonyl-l-hydroxyproline methyl ester N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER 1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Boc-L-Hyp-OMe BOC-HYP-OME